Hi Reddit! We’re the editors for Science Advances, an open access journal that accepts longer research articles (up to 6,000 words). Since our launch in February of 2015, we’ve published more than 1,500 papers and have a number of articles with tens (and even hundreds) of thousands of downloads, and hundreds of citations. As we mature as a publication, we continue our interest in areas of great scientific breakthroughs and innovation on both broad and disciplinary-specific levels. The journal is broadly organized in the areas of life and biological sciences, earth and environmental sciences, and physical and materials sciences. This month our publications range from water on the moon to the diverse interests of people who participated in the Women’s March to the internal GPS of seabirds. Feel free to ask us about what makes for a good research article, what topics we’re interested in, what questions we find most intriguing, and anything about open access. We’re also happy to chat about what makes us different and unique as an open access journal of AAAS, and what the editorial process here is like. We have editors Kip and Warren here to answer your questions as well as the managing editor Philippa Benson. What do you want to know about publishing and open access? We’ll be back at 2 pm ET to answer your questions, Ask us anything!
Hi Reddit, I’m Elijah Meeks. I wrote D3.js in Action and I just open sourced Semiotic, a data visualization framework focused on information modeling. I used to do data visualization in the digital humanities, including projects like ORBIS, Kindred Britain and the Digital Gazetteer of the Song Dynasty. Now I work at Netflix visualizing user behavior, algorithm performance and just big data more generally. Lately I’ve been pushing for the community to take a critical look at professional data visualization: how we design roles, how data visualization is seen by leadership and how we evaluate data visualization products. Proof of Life Follow me on Twitter Read my pieces on Medium Some examples of my work: My Blocks A visualization of Archer ORBIS - Geographic and Transportation Data Visualization of the Roman Empire A timeline of US Wars EDIT: Okay I came back and responded to a few more things and it was totally worth it.
Thanks for the great questions, Reddit! We’re done answering for the day and are off to finish preparations for tomorrow’s Earth Gravity Assist maneuver. Tomorrow, NASA’s asteroid-hunting spacecraft, OSIRIS-REx, will fly by Earth and use the planet’s gravitational pull to slingshot itself onto a new trajectory. This maneuver, called an Earth Gravity Assist (EGA), will put the spacecraft on course to rendezvous with a primitive, near-Earth asteroid named Bennu. The spacecraft will reach Bennu next year, map the asteroid, and collect a sample of surface material (called regolith) that will be returned to Earth for study in 2023. This mission will bring the largest sample of space material to Earth since the Apollo missions’ lunar samples. We’re a group of scientists and engineers based at the University of Arizona—home to the mission’s Principal Investigator’s office and the Science Processing Operations Center—ready to answer your questions about OSIRIS-REx, EGA, and the mission to collect some of the oldest material in the solar system. We’ll be online from 1 to 3 pm PST (4 to 6 pm EST). Ask us anything! Proof: https://www.asteroidmission.org/reddit-ask-us-anything-earth-gravity-assist/ Dr. Dante Lauretta, OSIRIS-REx Principal Investigator Sara Knutson, OSIRIS-REx Science Operations Lead Engineer Dr. Ellen Howell, OSIRIS-REx Senior Research Scientist, Asteroid Spectroscopy Joshua Nelson, OSIRIS-REx Science Operations Engineer Anjani Polit, OSIRIS-REx Mission Implementation Systems Engineer Heather Enos, OSIRIS-REx Deputy Principal Investigator Dr. Lucy Lim, OSIRIS-REx Assistant Project Scientist
Hello everyone. My name is Andy Kirk and I am a UK-based freelance data visualisation specialist. I do dataviz design consultancy, run training workshops, write books, give talks, undertake research work, lecture at Imperial College and I am the editor of visualisingdata.com. I also provide data visualisation services to the Arsenal FC performance team. You can find me on the web, on Twitter, Facebook and Instagram. I launched visualisingdata.com at start of 2010 to continue learning, research and writing about the subject. It won (gold, 2015) and lost (silver, 2016) awards at the last two Kantar Information is Beautiful awards event. I tend to be known for my list-making, with my ‘Best of…’ monthly and ’10 most significant developments’ posts quite popular as well as my ‘Little of visualisation design’ #LittleVis series. I also try to compile useful data resources for folks trying to make sense of all the options out there, such as dataviz tools, the chartmaker directory and dataviz books. Since I became a freelance professional in 2011 I have focused, primarily, on providing data visualisation consultancy and training workshops – of which I have delivered over 210 public and private training events across the UK, Europe, North America, India, South Africa and Australia. You can see my past clients listed here. In July 2016, I released my second book entitled “Data Visualisation: A Handbook for Data Driven Design”, published by Sage. So that’s me in text form here’s proof that I am actually me. ** Update @ 6:30pm (BST): I’m back, let’s do this **
Our recent publication was recently posted here: https://www.reddit.com/r/science/comments/6xs76y/duke_university_scientists_have_created_a_lethal/. We’ve been working on this project for three years now and would love to answer any related questions. This project is a combination of global health and biomedical engineering. We’re really excited by our most recent proof-of-concept and are planning more exciting experiments. Feel free to just generally ask about anything biology-related as well. Answering questions will be: Robert Morhard, Robert obtained a BS in Biomedical Engineering and Materials Science and Engineering from Carnegie Mellon University in 2012. In 2014 He received an MS in Biomedical Engineering from the Swiss Federal Institute of Technology - Zurich At Duke he works on developing a low-cost ablative tumor therapy for use in resource-limited settings. Corrine Nief Corrine obtained a BSc in Engineering with minors in Math and Chemistry from Baylor University. She was a summer researcher at Oak Ridge National Lab studying protein structure dynamics with super-computing. Later, she studied mitochondrial protein energetics at The National Institutes of Health. Now at Duke, her research is focused on developing low-cost cancer treatments for cervical and breast cancer. Carlos Barrero Castedo Undergraduate researcher, Duke University Jenna MuellerJenna received a B.S. degree in bioengineering with a minor in global health technologies from Rice University, and completed both an M.S. and Ph.D. in biomedical engineering at Duke University. Currently, Jenna is a postdoctoral researcher, who is interested in the intersection of biomedical engineering and global health. Specifically, she is interested in developing low cost optical devices and therapies to diagnose and treat cervical cancer in resource limited settings. Here is a direct link to our paper: https://www.nature.com/articles/s41598-017-09371-2 Here is a summary of the paper: https://www.acsh.org/news/2017/09/03/ethanol-lethal-injection-tumors-11779 We will be back at 1 pm Et to answer your questions, ask us anything!
ACS AMA Hey Reddit folks! My name is Charley Trowbridge and I am the Director of Peer Review Operations at the ACS. Along with my group, which consists of 15 team members distributed around the country and the globe, I am responsible for the support and maintenance of the peer review system that the ACS uses for all of its journals and books, and for the administrative support of our ca. 500 worldwide editorial offices. We strive to ensure that submitted content receives swift and thorough review, and are constantly looking for ways to improve our processes and policies to make submitting to ACS journals as easy as possible, while maintaining the highest possible quality of review experience. Recently we have also dedicated ourselves to developing the ACS Reviewer Labhttps://www.acsreviewerlab.org/, which is a free online interactive course that we have developed and launched to educate researchers on the principles of quality peer-review. Anyone can take the course, which takes about four hours to complete, in total. You can go through the six modules of the course at your own pace, and have 30 days to complete it. Also, September 11-17 is Peer Review Week - follow the conversations via #PeerRevWk17 on Twitter. I have been at the ACS for 11 years, and have been involved in the development and implementation of web-based peer review for about 16 years. Before coming to the ACS I worked for many of the major science publishers in a variety of roles and capacities, and I have been involved in scholarly publishing for the past 35 years overall. I have a BA in comparative literature, with a concentration in German. I lived and worked in Germany for two years. Ask me anything about the peer review system and process at the ACS, about how we handle submissions, and about how ACS supports authors, reviewers, and editors. I’ll be back at 11am EDT (8am PDT, 3pm UTC) to start answering your questions. Logging in at 11am EDT. Logging off at 12:31pm EDT.
Hello Reddit! We are: Hakhamanesh Mostafavi: Graduate student in biology at Columbia University Molly Przeworski: Professor of biology at Columbia University Joe Pickrell: CEO at personal genomics company Gencove and professor at the New York Genome Center. We are a few of the authors of a recent paper Identifying genetic variants that affect viability in large cohorts where we sought to use biomedical data sets to learn about mutations that affect survival. This paper was covered in a number of news outlets with titles like Massive genetic study shows how humans are evolving, and there was a great discussion of the paper on r/science What does it mean for humans to still be evolving? For a species to evolve simply means that mutations—the accidental changes to the genome that happen in the process of copying DNA—are increasing or decreasing in frequency in the population over time. Our basic idea was that mutations that affect the chance of survival should be present at lower frequency in older individuals. For example, if a mutation becomes harmful at the age of 60 years, people who carry it have a lower chance to survive past 60, and so the mutation should be less common among those who do. We therefore looked for mutations that change in frequency with age among around 60,000 individuals from California (as part of the GERA cohort) and around 150,000 from the UK Biobank. Across the genome, we found two variants that endanger survival in these individuals: (i) a mutation in the APOE gene, which is a well-known risk factor for Alzheimer’s disease, drops in frequency beyond age 70, and (ii) a mutation in the CHRNA3 gene, associated with heavy smoking, starts to decrease in frequency at middle-age in men.We found genetic mutations linked to a number of diseases and metabolic traits to be associated with survival: individuals who are genetically predisposed to have highertotal cholesterol, LDL cholesterol, risk of heart disease, BMI, risk of asthma, or lower HDL cholesterol, tend to die younger than others. Perhaps more surprisingly, we discovered that people who carry mutations that delay puberty or the age at which they have their first child tend to live longer. Thanks for having us, this was a lot of fun
Every day I work on the cutting edge of science and technology and I love it. Our team at the U.S. Naval Research Laboratory, works specifically with advanced optical imaging technologies which work to help map the ocean floor. It is my passion for the science and for mentoring others to help to navigating the maze of challenges, opportunities and achievements in the field. Have a question on the latest in active imaging research? Are you looking to make your own impact on the science community? I will be online at 1:00 pm to answer your questions – Ask Me Anything!
Hi Reddit, my name is King-Wai Yau, and I’m a neuroscientist at the Johns Hopkins University School of Medicine studying sight and smell! I started out in medical school at the University of Hong Kong but soon switched back to basic science and came to study in the U.S I have been studying vision for over 40 years, focusing on its first step, in which light interacts with the rod and cone receptor cells of the retina, initiating a complex biochemical/biophysical process which your brain eventually interprets as vision. However, we now know that additional photoreceptor cells beyond the rods and cones you learn in school actually exist in the retina. These newly found cells mediate eye functions unrelated to creating images, like constricting your pupil in response to changes in light. These non-rod/non-cone photoreceptors are important for helping us appreciate the progress of the day and, for example, in enabling us to get over jet-lag when traveling across time zones. Recently, my research has focused on understanding how light-induced pupillary constriction in mouse eyes can occur without the brain. Unlike in humans, mice’s pupils can constrict without an obligatory connection to the brain because light-detecting pigment, present in the iris’ sphincter muscle, responds directly to light. These findings shed light on the evolutionary path of the pupillary light reflex in vertebrates, which is essential for regulating light entry into the eye especially under bright conditions. Outside of the lab, although I hardly watch any commercial television, I would compulsively put aside work in the evening to watch Nature and Nova programs when they come up on Public Television. Any knowledge about biology, physics and chemistry is fair game to me! Check out my latest research here I’ll be back at 1pm ET today to answer your questions.
Hello, I am a medical epidemiologist and infectious disease doctor at CDC in the Waterborne Disease Prevention Branch. I work to prevent and stop infections caused by free-living amebas, which are single-celled organisms found in the environment, in water and soil. They cause diseases ranging from a type of encephalitis, or brain infection, to serious eye infections. I support epidemiologic, laboratory, and communication activities related to free-living ameba infections. Acanthamoeba is a free living ameba that can get on your contact lenses, and lead to a painful and disruptive infection called Acanthamoeba keratitis (AK). AK can lead to vision problems, the need for a corneal transplant, or blindness. Luckily, AK and other contact lens-related eye infections are largely preventable. So while I spend a lot of time working on specific free-living ameba infections, I also work with the CDC Healthy Contact Lens Program to help people learn about contact lens-related eye infections and the healthy habits that can reduce your chances of getting an eye infection. For more information about the CDC Healthy Contact Lens Program and our contact lens recommendations, visit our website: https://www.cdc.gov/contactlenses/index.html. I’ll be back at 1 pm to answer your questions, ask me anything!
We are SynTouch: the world leader in the technology of human touch. We invented the only sensor in the world that endows machines with the ability to replicate the human sense of touch. We call this emerging field Machine Touch. Like machine vision, it requires a combination of sensors and algorithms to take a human sense, capture it and allow us to do useful things with tactile information. One core application of our technology is quantifying dimensions of touch - we’ve created a taxonomy called the SynTouch Standard® that consists of fifteen dimensions humans feel. The information is captured by our BioTac Toccare® which Automakers, Apparel and Consumer Electronics companies use to define and improve the haptics of their products. Analogous to the use of digital color meters to capture RGB values and drive product manufacturing decisions to ensure they ‘look right’, our technology provides information to ensure products ‘feel right’. Our technology also functions as the input for haptic displays for VR and telerobotics. This allows us to drive haptic displays with real-world data for anything from a surgical robot to a gaming device – and we’ve worked with both! We’re also pursuing long-term projects to command robotic hands with tactile sense and reflexes. Our sensors allow robot hands to handle fragile objects better than currently available systems – one prime use case that we’re pursing now deploying this technology in prosthetics to allow amputees to handle fragile objects without dropping or crushing them. SynTouch was founded in 2008 by Professor Gerald Loeb, and Ph.D. students Matthew Borzage, Jeremy Fishel, and Nicholas Wettels who were at the University of Southern California. We’ve been recognized by Popular Mechanics, The Robot Report, and the World Economic Forum… Happy to answer more questions, but we’re getting busier with foot traffic right now. Thank you for your interest!
Hi Reddit, My name is Johannes Hegemann and I am Professor of Microbiology and Head of the Institute for Functional Microbial Genomics at the Heinrich-Heine-University in Düsseldorf, Germany. And my name in Katja Mölleken and I am a Senior Postdoctoral Fellow at the Institute for Functional Microbial Genomics at the Heinrich-Heine-University in Düsseldorf, Germany. Our research focuses on the molecular mechanisms that enable the pathogenic bacteria Chlamydia trachomatis and Chlamydia pneumoniae to infect their human hosts. This month, we published a study titled “Acquisition of Rab11 and Rab11-Fip2 – A novel strategy for Chlamydia pneumoniae early survival” in the journal PLOS Pathogens. Infection begins when the chlamydiae recognize specific receptors on their target cells, which triggers uptake of the bacteria. Once inside the cell, they establish a membrane-bound compartment termed an inclusion, in which they multiply before being released to infect new human cells. In our study we found that the nascent chlamydial inclusion actively recruits specific host proteins called Rab proteins into its membrane. These proteins define the inclusion as a so-called recycling endosome vesicle, within which the Chlamydiae hide out, so as to avoid degradation by the host cell’s waste disposal system, the lysosome. Our findings help to understand how Chlamydiae establish the intracellular niche which is essential for their survival and release. We will be answering your questions at 1pm ET – Ask us Anything!
Happy Eclipse Day r/science! We’re here early to answer any last minute questions you might have about today’s historical event. Here are your AMA eclipse chat hosts: Alexa Halford is a heliophysics scientist originally from Chippewa Falls WI (go Pack go!). She is a prime example of what happens when you go to college in MN and take up space… You become a space physicist. Because she got her PhD in Oz, you sometimes hear her say x,y, zed instead of x,y, zee. Although she has worked on science questions throughout the solar system, today she sticks a bit closer to home studying the Earth’s magnetic field and the impacts of space weather events. She was part of a huge NASA AMA yesterday on the eclipse with a bunch of scientists posting as /u/NASASunEarth. Angela Fritz is The Washington Post’s deputy weather editor and an atmospheric scientist who hails from the city of rock and roll and burning rivers – Cleveland, Ohio. She knew from a young age that weather was her true calling. After receiving a B.S. in meteorology from Valparaiso University and an M.S. in earth and atmospheric science from the Georgia Institute of Technology, Angela worked as a meteorologist at CNN in Atlanta and Weather Underground in San Francisco. When she’s not forecasting hurricanes or reading the latest climate science papers, Angela enjoys outdoor adventures, public transportation, and Oxford commas. We’re going to get started at 10 a.m. ET so get those questions ready! AMA! Proof EDIT: And that’s a wrap for now! We may come back later to answer additional questions, but in the meantime, enjoy this historic day, be safe! And if you want more info, follow live coverage from The Washington Post, who is featuring coast-to-coast coverage and a livestream. EDIT 2: One more link: Here is every total solar eclipse happening in your lifetime. Enter your birth year and we’ll tell you when and where.
My most recent column (https://undark.org/article/soy-formula-babies-endocrine-disruptor/) looked at soy formula (and other soy products) which contain a remarkably high level of hormonally active compounds called phytoestrogens. I was interested in the idea that by feeding soy to babies - a constant diet at an age critical in human development - we might be running an inadvertent experiment on those children, perhaps alerting their reproduction systems. The scientists I talked to agreed that that’s a real possibility. There are studies showing that soy diets can affect gene expression in the vaginal cells of female girls, for instance, that there are other longer term studies showing changes in menstruation and other effects. It’s an issue I’d like to follow further. Part of the reason I was interested in that aspect of soy exposure is that I’m a toxicology writer. I’ve been researching and writing about toxic substances for a decade, as the author of The Poisoner’s Handbook, but also as a blogger for Wired and for The New York Times, where I wrote an online column called Poison Pen. I started out being very focused on acute toxicity but I’ve more recently become interested in low-dose toxicology - the question of what chronic exposure to a very low dose of a compound (say arsenic in rice or drinking water) means in terms of public health. The question of every day exposures and how we navigate them really fascinates me and is part of my current book project, which follows the story of America’s first great food safety chemist at the turn of the 20th century. I’m here today from 1 pm-3:00 pm EST to answer questions about chemical exposures in our everyday life, questions of natural versus synthetic compounds, and when it’s worth paying attention. Looking forward to hearing from you!