Hepatoblastoma, the most common liver tumor of childhood is generally treated with chemotherapy and surgery. More than half of the patients are unresectable at time of diagnosis. Therefore, neo-adjuvant chemotherapy has been the mainstay of treatment. However, long-term effects of systemic chemotherapy and inadequate response to conventional chemotherapy have been major issues in management of hepatoblastoma. As a result, attempts towards local treatment options were made such as transarterial chemoembolization (TACE) which allows tumor necrosis both via vascular occlusion and chemotherapy. Here we present a seven-year follow-up results of an infant treated with neoadjuvant chemotherapy, drug-eluting bead-TACE and surgery.