HEPATOBLASTOMA TREATED SUCCESSFULLY WITH DRUG-ELUTING BEAD TRANSARTERIAL
CHEMOEMBOLIZATION: OUTCOME OF SEVEN-YEAR FOLLOW-UP
Abstract
Hepatoblastoma, the most common liver tumor of childhood is generally
treated with chemotherapy and surgery. More than half of the patients
are unresectable at time of diagnosis. Therefore, neo-adjuvant
chemotherapy has been the mainstay of treatment. However, long-term
effects of systemic chemotherapy and inadequate response to conventional
chemotherapy have been major issues in management of hepatoblastoma. As
a result, attempts towards local treatment options were made such as
transarterial chemoembolization (TACE) which allows tumor necrosis both
via vascular occlusion and chemotherapy. Here we present a seven-year
follow-up results of an infant treated with neoadjuvant chemotherapy,
drug-eluting bead-TACE and surgery.