Objective: To determine prevalence of asthma in Pune and its relation to family history of allergic disease. Study Design: Cross-sectional study in two schools of Pune. Method: International Study of Asthma and Allergy in Childhood (ISAAC) based questionnaire was administered to 815 parents of students of 2 selected schools between ages of 5-15 years. Responses were analyzed and children with history suggestive of asthma were examined, investigated at a tertiary teaching hospital. Results: prevalence of asthma was 6.13%. Prevalence in males was 6.36% and in females was 8.05% (p= 0.639). Prevalence in English medium school was 7.36% as compared to Marathi medium school of 3.8%. Family history of asthma and allergic disease had strong association with asthma. PEFR at time of enrolment was decreased in many children irrespective of symptoms. Conclusion: Prevalence of asthma was 6.13%. Family history is strong determinant of asthma. Keywords: Asthma Prevalence, Family History, PEFR Correlation.