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COVID-associated non-vasculitic thrombotic retiform purpura of the face and extremities: A case report
  • +16
  • Connor Bunch,
  • Nuha Zackariya,
  • Anthony Thomas,
  • Jack Langford,
  • Michael Aboukhaled,
  • Samuel Thomas,
  • Aida Ansari,
  • Shivani Patel,
  • Hallie Buckner,
  • Joseph Miller,
  • Christy Annis,
  • Margaret Quate-Operacz,
  • Leslie Schmitz,
  • Joseph Pulvirenti,
  • Jonathan Konopinski,
  • Kathleen Kelley,
  • Samer Hassna,
  • Luke Nelligan,
  • Mark Walsh
Connor Bunch
Henry Ford Hospital

Corresponding Author:[email protected]

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Nuha Zackariya
Indiana University School of Medicine-South Bend
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Anthony Thomas
Indiana University School of Medicine-South Bend
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Jack Langford
Saint Joseph Regional Medical Center Mishawaka Campus
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Michael Aboukhaled
Saint Joseph Regional Medical Center Mishawaka Campus
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Samuel Thomas
Saint Joseph Regional Medical Center Mishawaka Campus
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Aida Ansari
Saint Joseph Regional Medical Center Mishawaka Campus
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Shivani Patel
Saint Joseph Regional Medical Center Mishawaka Campus
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Hallie Buckner
Saint Joseph Regional Medical Center Mishawaka Campus
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Joseph Miller
Henry Ford Hospital
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Christy Annis
Saint Joseph Regional Medical Center Mishawaka Campus
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Margaret Quate-Operacz
Kidney Care of Michiana
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Leslie Schmitz
Kidney Care of Michiana
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Joseph Pulvirenti
Saint Joseph Regional Medical Center Mishawaka Campus
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Jonathan Konopinski
South Bend Medical Foundation
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Kathleen Kelley
Beacon Medical Group
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Samer Hassna
Saint Joseph Regional Medical Center Mishawaka Campus
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Luke Nelligan
Marian University College of Osteopathic Medicine
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Mark Walsh
Saint Joseph Regional Medical Center Mishawaka Campus
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Abstract

SARS-CoV-2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID-19 illness. Aggressive anti-COVID-19 therapy with a high-dose steroid regimen led to rapid recovery. This immuno-thrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.
12 Oct 2022Submitted to Clinical Case Reports
12 Oct 2022Submission Checks Completed
12 Oct 2022Assigned to Editor
18 Oct 2022Reviewer(s) Assigned
20 Nov 2022Review(s) Completed, Editorial Evaluation Pending
20 Nov 2022Editorial Decision: Revise Minor
28 Nov 20221st Revision Received
29 Nov 2022Submission Checks Completed
29 Nov 2022Assigned to Editor
29 Nov 2022Review(s) Completed, Editorial Evaluation Pending
08 Dec 2022Editorial Decision: Accept