We present the case of a patient with patch-stage mycosis fungoides who developed ulcerative tumors compatible with large cell transformation. Tumor cells were positive for CD30 and CXCR3 and negative for CCR3, and subsequently exhibited spontaneous regression. Thus, large cell transformation in early mycosis fungoides may not indicate poor prognosis.
Retrieval of central venous catheters fragments often puts us in front of different situations. Having more techniques available for strategic planning of the procedure is imporatnt. The authors propose the simultaneous use of two different approaches for the recovery of a CVC fragment from the pulmonary artery.
4 cases have been reported from a tertiary referral hospital in Tehran, of which 3 have confirmed COVID-19 infection and one has been highly suspicious. The cases describe different cardiovascular presentations that can be linked to COVID-19 infection, including myocardial infarction, in-stent restenosis, myopericarditis and tamponade, and aortic dissection.
This is a report of an 8-year-old male with Schwartz-Jampel syndrome with severe obstructive sleep apnea. Dental findings include severe maxillary crowding, posterior crossbite, missing lower incisors, and supernumerary lower premolar. Significant craniofacial characteristics include Type I skeletal relationship with bimaxillary hypoplasia, hyperdivergent skeletal pattern, severe constriction of dental arches.
During coronavirus disease 2019 (COVID-19) pandemic, coinfections with other viral infections are not uncommon, but concomitant atypical bacteria are rare. Herein, we describe a young female COVID-19 patient who developed acute cold agglutinin disease secondary to Mycoplasma pneumoniae. Using an azithromycin-containing COVID-19 therapeutic regimen, both pneumonia and anemia resolved uneventfully.
A 63 year old patient with chronic lymphocytosis and neutropenia is described. A bone marrow biopsy showed a markedly hypercellular specimen with an interstitial and intrasinusoidal lymphoid infiltrate. Immunohistochemistry and immunophenotyping identified these as LGLs. With paucity of erythropoiesis diagnosis of LGL leukemia with pure red cell aplasia is reached.
Typical form of Hemolytic Uremic Syndrome is caused most commonly enterohemorrhagic E. coli strain O157:H71. Here we report a unique case of HUS secondary to enteropathogenic E. coli infection, with a discussion on the diagnosis of HUS and how it is distinguished from other thrombotic microangiopathies (TMAs).
A 24-year-old male presented with radiating back pain and progressive neurological deficit. MRI revealed spinal epidural tumor at the thoracolumbar junction. He underwent decompression and excisional biopsy. Histopathology and immunohistochemistry identified it as diffuse large B-cell lymphoma. He received chemotherapy and is asymptomatic at one-year follow-up.
Epidermolytic hyperkeratotic EN (epidermal nevus) is a rare variant of EN, which can be congenital or developed later in adulthood. A 23 years old female presented with a pathologic confirmed epidermolytic hyperkeratotic EN. Dermoscopy can be helpful in the diagnosis of EN, but not in differentiating the variant.
Neuropsychiatric systemic lupus erythematosus (NPSLE) is usually associated with a worse prognosis. However, there are few effective treatments for NPSLE. We described protein A immunoadsorption treatment for a patient with NPSLE. The patient’s brain lesions was improved rapidly after two sessions of protein A immunoadsorption combination with immunosuppressive agent treatment.
Although parathyroid tissue auto-transplantation is useful for preventing hypoparathyroidism during thyroidectomy, hyperparathyroidism may occur due to proliferation of the transplanted parathyroid tissue. Hyperparathyroidism due to the autografted parathyroid gland should be suspected in patients who undergone parathyroid auto-transplantation.
Posterior spinal surgery has the risk of perioperative respiratory complications. We describe the delayed diagnosis of an intraoperative pneumothorax in a teenage girl with idiopathic scoliosis scheduled for thoracolumbar posterior fusion. After an uneventful surgery, the oxygen saturation abruptly decreased to 65%. A chest x-ray showed a moderate pneumothorax.