IntroductionPulmonary sclerosing pneumocytoma is a rare group of benign pulmonary neoplasms that usually affects older adults over 50 years of age [1].  This neoplasm is more commonly seen in women, with female to male ratio of 5:1 and is predominantly seen in Asian ethnicities [2]. These tumors originate from type II alveolar pneumocytes and are hence classified as adenoma under the 2021 World Health Organization (WHO) classification of tumors [3]. They account for 3-5 percent of total benign lung tumors [4].One of the striking aspects of PSP is its clinical presentation, or rather the lack thereof in many cases. It is often discovered incidentally during routine chest imaging, such as chest X-rays or CT scans, due to its asymptomatic nature. However, when symptoms do occur, they tend to be non-specific, including cough, chest pain, or respiratory distress. This variability in clinical manifestation further complicates the diagnosis of PSP, as these symptoms overlap with those of other pulmonary conditions. Moreover, it is essential to consider the potential for malignant transformation, as a subset of PSP cases have exhibited aggressive behavior [5].Herein, we describe a case of a 73-year-old female who was found to have an incidental lung nodule. In view of the history of interval increase in the size of the lung nodule, the patient underwent a CT-guided lung biopsy, which was characterized as sclerosing pneumocytoma, and the patient was referred to thoracic surgery for subsegmental right middle lobe resection.

Varicella Zoster is a neurotropic virus which leads to acute varicella or it may lay dormant in the spinal root ganglion. Reactivation of varicella zoster causes Herpes Zoster (HZ) and occurs commonly in immunosuppressed conditions like COPD. Severity of Herpes Zoster is also higher among those with comorbidities like COPD. Even among COPD patients, the severity of HZ is said to be higher among those using oral corticosteroids than those using inhaled steroids due to greater immunosuppressive effect. It has also been found that incidence rate of COPD exacerbations, transient ischemic attack and stroke are higher among COPD patients with HZ compared to those without HZ. Herpes zoster vaccinations prevent reactivation of latent HZ and reduce the associated complications. Live attenuated and recombinant vaccines are available for vaccination among which recombinant vaccine is found to be more effective. The cost burden due to HZ among COPD patients was also higher compared to those without HZ. Childhood varicella vaccination is cost effective, however cost effectiveness of adolescent vaccination is unclear.

Silicosis unveiled: Improving diagnostic accuracy and distinguishing it from tuberculosis: A case report from a low and middle-income countryChapagain, Sanskriti1 , Shrestha,Abhigan Babu2 ,Shrestha ,shumneva 3,Shrestha, sajina4,jaiswal ,vikash5,yadav,Hritik Raj 2, Shrestha ,Nilasma61. Devdaha Medical College and Research Institute, Bhaluhi, Rupandehi, Nepal2.M Abdur Rahim Medical Medical College Hospital, Department Of Internal MedicineDinajpur, Bangladesh3. Tribhuvan University Institute of Medicine Maharajgunj Medical Campus ,Nepal4. KIST Medical College, Department Of Internal Medicine, patan Imadol, Lalitpur,Nepal5. Medical AMA School of Medicine, Medicine Bangkal makati, Philippines Makati City, Luzon6.Kathmandu Medical College,Kathmandu,NepalCorresponding author :Chapagain,SanskritiDevdaha Medical College and Research Institute, Bhaluhi, Rupandehi, [email protected]

Harlequin Ichthyosis is a rare autosomal recessive disorder occurring in 1: 3,000,000 birth characterized by thick keratin skin with scaly appearance. Preterm deliveries, early marriage and consanguinity of marriage are some risk factors. Antenatal checkup of DNA for ABCA12 mutation helps in diagnosis but USG in places where not available.