Thrombocytosis with Acquired von Willebrand Disease in an Adolescent
with Sickle Cell Disease
Thrombocytosis is common in children with sickle cell disease (SCD).
Reactive thrombocytosis must be distinguished from myeloproliferative
disorder or inherited thrombocytosis syndrome. We present an adolescent
with hemoglobin SS and thrombocytosis associated with increased
frequency of pain, priapism, and acquired von Willebrand disease.