Tension-free trans-obturator tape enhanced thermodynamic efficacy of the
bladder in stress urinary incontinence patients: a retrograde
observational study
Abstract
Objective In contrast to the well-recognized benefit of trans-obturator
tape (TOT) to urine continence, if the TOT-enhanced urethra resistance
results in modified voiding functions in stress urinary incontinence
(SUI) patients is not adequately investigated. Design and setting
Urodynamic investigations were retrograde analyzed in a tertiary
referral hospital. Population A total of 26 female SUI patients Methods
The area enclosed by the loop trajectory (Apv) in a pressure-volume
analysis (PVA) which represent the work performed in each voiding cycle
was retrospectively analyzed Main outcome measures The Apv of female SUI
patients before and after the TOT were analyzed. Results When compared
with the pre-operative control, the Apv was significantly increased
post-operatively. The TOT-enhanced Apv was accompanied by increments in
the mean urethra resistance (Rv) and mean voiding pressure (Pv) but
unaffected voided volume (Vv) and voiding time (Tv). Moreover, the
TOT-induced Apv increase (ΔApv) displayed moderate correlations with the
changes in Rv and Pv (ΔRv and ΔPv, respectively) but no correlation with
the changes in Vv or Tv (ΔVv and ΔTv, respectively). Notably, the
TOT-induced ΔRv displayed a strong correlation with the ΔPv.
Conclusions: The thermodynamic efficacy of the bladder was enhanced
after the TOT; that could be attributed to that bladder develops an
elevated pressure gradient in response to the TOT-enhanced outlet
resistance during urine emission. Keywords: mid-urethra sling,
trans-obturator tape, stress urinary incontinence, urethra resistance,
thermodynamics, pressure-volume analysis Tweetable abstract The bladder
developed an elevated pressure gradient to the TOT-enhanced outlet
resistance; and herein enhanced the voiding efficacy.