Fanny Delehaye

and 12 more

Background The posttreatment period is a key part of the management of pediatric cancer care. At this period, psychosocial effects (scholarly and psychological difficulties) have been described in pediatric cancer patients and can be prognostic for the success of social reintegration. Psychosocial effects and their impact may be related to the household’s socioeconomic background. The aim of this study was to estimate psychosocial difficulties during the posttreatment period based on a social deprivation score. Design This study is based on a prospective multicentric study database, and focused on the children who had received psychosocial evaluation during their follow-up after cancer treatment since 01/01/2013. We retrieved data on their learning and psychological difficulties. Socioeconomic status of the household was estimated by a social deprivation score. Results 1003 patients were analyzed. Learning difficulties at school were noted in 22% of patients. A greater social deprivation was significantly associated with learning difficulty (OR=1.09 per unit of the deprivation score). Tumor relapse, treatment with hematopoietic stem cell transplantation, and diagnosis of a CNS tumor remained significant risk factors. In the subgroup analysis of children with CNS tumors, learning difficulties were increased and associated with greater social deprivation. By contrast, psychological difficulties were not associated with the deprivation score. Conclusion There is a link between SE status and learning difficulties in survivors of childhood cancer. Further investigations should be carried out to confirm these results for children with CNS tumors, which is the population of the greatest concern.

Oum-Keltoum Hadjou

and 5 more

Objective: To evaluate the prevalence of dysmenorrhea in adolescents and its impact on daily living. Design: A cross-sectional, questionnaire-based study Setting: Multicenter study in eight randomly selected high schools in France. Population: Randomly selected post-menarche girl pupils 15 –19 years Methods: Each girl was asked to complete a 50-item questionnaire. Main Outcome Measures: Dysmenorrhea severity was assessed with the Numerical Rating Scale (NRS) and Verbal Multidimensional Scoring System Scale (VMSS). Results: Questionnaires from 953 girls were analyzed (mean age: 16.9 years). The prevalence of dysmenorrhea was 92.9 % with 8.9 % describing their pain as severe. Impact on quality of life was significant: 43.3% of the girls reported school absences because of dysmenorrhea, 74.9% difficulties in attending classes and 77.2% difficulties in sports activities. Risk factors of severe dysmenorrhea (VMSS grade 3) in multivariate analysis were heavy menstrual bleeding (OR 2.02, 95%CI [1.12 ; 3.63] p=0.0192), early menarche (OR 0.68, 95%CI [0.57 ; 0.81] p<0.0001), chronic pelvic pain (OR 2.60, 95%CI [1.10 ; 6.11] p=0.0274), BMI (BMI<18, OR 1.94, 95%CI [1.03 ; 3.66] p=0.0335). Of the 50.4% who had consulted a physician, 45.4% had seen a general practitioner. Among the girls who had not consulted a physician, 55.1% reported that menstruation was a “woman’s burden”. Conclusion: Dysmenorrhea is highly prevalent in adolescents in France and has a real impact on daily life activities. As such, it should be treated as a public health problem with educational and information campaigns targeting the girls themselves, their families and healthcare professionals.