Objectives: This study aims to investigate incidence of nostril asymmetry and deviation of nasal bony pyramid and caudal septum and to examine their association with dominant hand in male adolescents. Methods: Totally 546 male healthy adolescents aged 15 to 17 years were included. Each participant was examined for presence or absence of nasal bone pyramidal deviation, caudal septal deviation, side of deviation, and nostril asymmetry. The dominant hand was recorded. Results: Of participants, 85 were aged 15 years, 291 were aged 16 years, and 168 were aged 17 years. Mean age was 16.148±0.667 years. Of all participants, 91% (n=497) were right-handed and 9% (n=49) were left-handed. Distribution of the dominant hand across age groups was comparable (p=0.921). In case of deviation to the right, 61.2% (n=74) were right-hand dominant, while 58.3% (n=7) of those with deviation to the left were left-hand dominant. According to hand dominance and size of nostrils, 92.1% (n=105) of those with a larger left nostril were right-handed and 7.9% (n=9) were left-handed. Conclusions: Male adolescents had a significant deviation of caudal septum to the right side with smaller right nostrils. However, hand dominance and side of deviation were not significantly associated with nasal bony pyramid and caudal septum.