Abstract
Proteomics is a collective approach using other “omics” technologies
for analyzing and identifying the function and structure of proteins
with greater precision. Along with the revolution in technologies and
increase in statistical computing models, proteomics has been cognate
promptly over the last ten years and enlightened on resolving complex
diseases. Identification of various protein biomarkers, expression
patterns of proteins in diseases, and the mechanism of pathogenicity,
there is a demand for Proteomics-based technologies. This article
profound impact on proteomics across diverse scientific domains,
including disease biomarker discovery, drug development, structural
biology, and functional genomics, complex biological systems, and
underscores the significance of various techniques, including mass
spectrometry, protein microarrays, SILAC, and iTRAQ. This review aims to
illustrate several technologies of proteomics with their principle, the
latest advancements, and their role in research.