4.1.2 Functional protein microarray
The emergence of protein domains with full-length functionality provides a way forward for Functional protein microarrays. The protein chips are utilized in a single experiment to examine the biochemical functions of the whole proteome [47]. Purified proteins are now being used to create functional protein microarrays, that allows to study the protein interactions with protein, lipid, drug, DNA and RNA. In yeast, protein kinases substrate specificity was first analyzes using functional protein microarray. Protein functions and disease biomarkers are now identified via functional protein microarray [49].