Chlorine dioxide is a potent oxidant with in vitro anticancer activity. Its precise mechanism of action has not been thoroughly explored, but it is proposed that it acts through the redox imbalance of cancer cells. Three patients were treated for metastatic cancer (kidney, prostate  and lymphoma), on a compassionate basis. We report lasting tumor response with a combination of oral, enema and/or intravenous chlorine dioxide, without side effects. The patients had refused conventional chemotherapy, radiation therapy or immunotherapy. This preliminary work suggest that chlorine dioxide and his free radicals might be the mediators. Chlorine dioxide is both a promising and unexpensive anticancer agent. Rigorous clinical trials are needed to confirm these preliminary results.

Keywords: Chlorine dioxide solution, cancer, reactive oxygen species, intermittent fasting, ketogenic diet