How we approach coagulopathy with vascular anomalies.
Some vascular anomalies can present with challenging hematologic
aberrations. Kaposiform hemangioendothelioma (KHE) may be complicated
with Kasabach-Merritt phenomenon (KMP) and stagnant blood flow in slow
flow malformations can promote activation and consumption of coagulation
factors which results in bleeding and clotting known as localized
intravascular coagulopathy (LIC). These patients can experience
significant morbidity secondary to pain due to thrombosis and are at
higher risk of hematologic complications during surgical procedures. No
standard of care has been established to prevent or manage these
complications. This review focuses on the management of coagulopathy in
children and adults with vascular anomalies.