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The role of nasal congestion as a defence against respiratory viruses
  • Ron Eccles
Ron Eccles
Cardiff University College of Biomedical and Life Sciences

Corresponding Author:[email protected]

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Introduction; This review discusses how nasal congestion may have benefits as a mechanism of defence against respiratory viruses. Methods; A literature research was conducted on respiratory viruses and nasal congestion, following a recently published review on how temperature sensitivity is important for the success of common respiratory viruses. Results; The literature reported that common respiratory viruses are temperature sensitive and replicate well at the cooler temperatures of the upper airways (32oC), but replication is restricted at body temperature (37oC). The amplitude of the phases of congestion and decongestion associated with the nasal cycle was increased on infection with respiratory viruses and this caused unilateral nasal congestion and obstruction. Nasal congestion and obstruction increase nasal mucosal temperature towards 37oC and therefore restricted the replication of respiratory viruses. Conclusion; Nasal congestion associated with the nasal cycle may act as a mechanism of respiratory defence against infection with respiratory viruses
25 Aug 2020Submitted to Clinical Otolaryngology
04 Sep 2020Assigned to Editor
04 Sep 2020Submission Checks Completed
09 Sep 2020Reviewer(s) Assigned
05 Oct 2020Review(s) Completed, Editorial Evaluation Pending
10 Oct 2020Editorial Decision: Accept
Jan 2021Published in Clinical Otolaryngology volume 46 issue 1 on pages 4-8. 10.1111/coa.13658