Case Report: Subsequent hypopharyngeal adenoid cystic carcinoma
accompanied by synchronous esophageal carcinoma following previous
squamous cell carcinoma in hypopharynx
Abstract
Background: The adenoid cystic carcinoma (ACC) barely arises in
sites other than the salivary glands. Its presentation in the
hypopharynx previously diagnosed as squamous cell carcinoma (SCC) is
entirely unexpected. Case Presentation: A man was presented
with a hypopharyngeal mass revealed by electronic laryngoscopy. Multiple
biopsies pathologically showed well to moderately differentiated SCC.
Six months after definitive concurrent chemoradiation, his endoscopy
showed a recurrent mass in the same region before and pathology of
gastroscopic biopsy showed moderately differentiated SCC of esophagus.
The mass was removed after radical dissection. Histologic examination
showed sheets and cords of tumor cells with basophilic matrix in
hypopharynx known as ACC and moderately differentiated esophageal SCC.
Conclusion: The documentation of metachronous ACC arising in
hypopharynx following previous SCC would further supports the concern
about multicomponent tumors in hypopharynx which is crucial in clinical
practice.