loading page

Discovery platforms for RNA therapeutics
  • Giulio Ciucci,
  • Luca Braga,
  • Serena Zacchigna
Giulio Ciucci
Author Profile
Luca Braga
Author Profile
Serena Zacchigna

Corresponding Author:[email protected]

Author Profile


RNA therapeutics are emerging as a unique opportunity to drug currently “undruggable” molecules and diseases. While their advantages over conventional, small molecule drugs, their therapeutic implications and the tools for their effective in vivo delivery have been extensively reviewed, little attention has been so far paid to the technological platforms exploited for the discovery of RNA therapeutics. Here, we provide an overview of the existing platforms and ex vivo assays for RNA discovery, their advantages and disadvantages, as well as their main fields of application, with specific focus on RNA therapies that have reached either phase 3 or market approval.
Submitted to British Journal of Pharmacology
30 Jan 2024Review(s) Completed, Editorial Evaluation Pending
02 Feb 2024Editorial Decision: Revise Minor
02 Mar 2024Submission Checks Completed
02 Mar 2024Assigned to Editor
13 Apr 2024Editorial Decision: Revise Minor
14 Apr 20242nd Revision Received
15 Apr 2024Submission Checks Completed
15 Apr 2024Assigned to Editor
19 Apr 2024Editorial Decision: Accept