The sealing effect of the magnetic-sealing uterine manipulator in
patients with early-stage cervical cancer
Abstract
Objective: To assess the sealing effect of a Magnetic-Sealing Uterine
Manipulator (MUM) in isolated uterus. Design: Non - intervention study.
Setting: This study was conducted at the First Affiliated Hospital of
Xi’an Jiaotong University from November 2019 to April 2021. Population:
Patients with early-stage cervical cancer who underwent radical
laparotomy hysterectomy. Methods: The MUM closure test (group 2) and the
control test (right-angle forceps closure tests, group 1 and 3) were
carried out in an isolated uterus. Main outcome measure: DNA ploidy
analysis system was used to analyze the exfoliated cells. Statistical
analysis was performed using Wilcoxon signed rank test to assess the
sealing effect of MUM. Results: We identified 36 patients. None regional
node metastasis was found in all cases and only one of their tumors was
larger than 4.0 cm. The mean numbers of exfoliated tumor cells in groups
1, 2, and 3 were 1, 1, and 2, respectively. There was no significant
difference in the number of exfoliated cells between group 1 and group 3
(p=0.476). We merged the results of group 1 and 3. Furthermore, there
was significant difference between right-angle forceps closure tests and
MUM closure test (p=0.022). Conclusion: The sealing effect for MUM was
better than the right-angle forceps. The MUM can effectively seal the
cervical cancer cells in the cup cover and avoid the dissemination of
tumor cells.