Oral mucositis in children with hematologic tumors undergoing
chemotherapy: A case series
Abstract
Oral mucositis (OM) is the most common local adverse event of
chemotherapy treatment and leads to a debilitating condition from the
patient’s perspective. The aim of this study is to report nine cases of
severe OM over 10 weeks after initiating chemotherapy in pediatric
patients with leukemia. All patients showed changes in normality of
hematological data in most week. The most used chemotherapeutic agents
were aracytin, etoposide and methotrexate. Saliva and lips were the most
affected items. Well-designed observational studies are needed to better
understand the risk factors for developing severe OM.