Mepolizumab -- therapeutic strategy for a paediatric patient with
eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as
Churg-Strauss syndrome) is classified as an anti-neutrophil cytoplasmic
antibody (ANCA)-associated small vessel vasculitis. It is a multisystem
disorder and can affect every organ system. EGPA is a rare disease, with
an estimated prevalence of 1/70,000–100,000 in Europe. As its onset
usually occurs in adulthood, data from paediatric patients are limited.
We present here a very rare practical EGPA clinical case involving a
paediatric patient. Presently, data on mepolizumab usage in paediatric
patients are limited, with only a few case reports published.