Extracranial carotid ultrasound evaluation for ischemic moyamoya disease
in adults with different collateral circulation patterns
Abstract
OBJECTIVE: To explore the possibility and application value of
extracranial carotid ultrasound in assessing the progress of MMD.
METHODS: We retrospectively analyzed the extracranial carotid ultrasound
and DSA data of 89 cases of 53 patients with MMD (moyamoya group) and 90
cases of 45 control patients (control group). According to the DSA data
of the moyamoya group, collateral circulation patterns’ grade and Suzuki
stage were performed. We analyzed the correlation between collateral
circulation patterns and Suzuki stage, and compared the difference of
hemodynamic parameters between different grades of collateral
circulation patterns. RESULTS: (1) As the Suzuki stage increased, the
grade of the collateral circulation pattern subsequently increased. (2)
Compared with the control group, the PSV of ICA in the moyamoya group
was lower (P<0.01),but the RI value of CCA and PSV of VA was
increased (P<0.05). And the differences in hemodynamic
parameters of ECA (including PSV and RI) were not statistically
different. (3) Comparing hemodynamic parameters between the different
grades of collateral circulation patterns of the control group, Grade 2
showed higher PSV of VA compared with Grade 1 (P <0.05); Grade
3 showed lower RI of ECA compared with Grade 1 and Grade 2 (P
< 0.05). CONCLUSION: There is a correlation between collateral
circulation patterns and Suzuki stage in adult ischemic MMD. There are
differences in the hemodynamic parameters of extracranial carotid
ultrasound in different grades of collateral circulation patterns.
Extracranial carotid ultrasound can assess the progress of MMD in a
timely, effective and convenient manner.