Gastroenterological disorders increase the prevalence of Overactive
Bladder in females at various ages
Abstract
ABSTRACT Objective: In this study we aimed to determine the coexistence
of overactive bladder in patients with gastroenterological disorders
including hepatitis, cirrhosis and IBD. Materials and Methods: we
prospectively collected the data of patients who admitted to the
outpatient clinic of department of gastroenterology at xxx hospital
between May 2017 and February 2019. All patients with chronic
gastroenterological disorders such as hepatitis and irritable bowel
syndrome willing to participate the study after the verbal consent were
included the study Results: A total of 289 female patients were included
the study. The mean age of the patients was 49.9 ±13 years. The mean BMI
value was 27.9± 4.5 kg/m2. Among 289 patients, 135 (46.7%) had
Hepatitis B, 53 (18.3%) had ulcerative colitis, 35 (12.1%) had Crohn’s
disease, 22 (7.6%) had autoimmune hepatitis, 19 (6.6%) had primer
biliary cirrhosis, 13 (4.5%) had Hepatitis C and 12(4.2%) had celiac
disease. The mean age of patients was similar between patients having
OAB-v8 higher and lower than 8 (p=0.46). However, patients having OAB
score>8 had higher BMI compared to patients who had OAB
score <8, 29.1 ±5 vs. 27.2 ±4.1 kg/m2, p=0.001. In
multivariate regression analysis, BMI was the sole indicator of OAB
(p=0.001) whereas age (p=0.46), menopause status (p=0.33), smoking
status (p=0.97) were not. Conclusion: The incidence of OAB in our
patient cohort was higher than the reported incidence which might
suggest evaluation patients with gastrointestinal disorders in terms of
overactive bladder on routine follow-up.