A previously healthy 68-year-old woman with abrupt weakness in her left limbs underwent transthoracic echocardiography for paroxysmal atrial fibrillation, which showed normal left ventricular function and no abnormalities except for left atrial dilation. However, transesophageal echocardiogram showed two leaflet-shaped loose left atrial masses were attached to the atrial septum near the oval fossa. Further CDFI found a few small vessels at the base, confirming the atrial myxoma. Surgery was performed to resect the intracardiac mass, and the histologic examination showed cardiac myxoma with glandular structure.