Dietary phytochemicals that can extend longevity by regulation of
metabolism
- jie shen,
- Jianying Shan,
- Boying Liang,
- Dake Zhang,
- Motao Li,
- Hao Tang,
- Lichao Zhong
Abstract
Diet provides energy and nutrition for human survival, and also provides
various joy of taste. Extensive studies have shown that the major
components of diet, such as protein, carbohydrate and fat, play
important roles in regulating aging and longevity. Whether other dietary
ingredients can help prevent aging and extend longevity is a very
interesting question. Here based on recent findings, we discussed
dietary plant ingredients that can extend longevity by regulation of
metabolism, targeting TRP channels, mitophagy, senescence pathways and
circadian rhythms. Better understanding of the detailed effects and
mechanisms of dietary ingredients on longevity regulation, would be
helpful for developing new intervention tools for preventing aging and
aging related diseases.