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\label{tab:2}Cross-validation accuracy. The percentage of correctly imputed two-field alleles is shown for each method at each HLA locus in each of four major populations from the cross-validation analysis with the multi-population reference panel. The number of individuals used for validation in each population at each HLA locus is also shown. *Method does not support this locus.
No. validation Method
Population HLA locus individuals HIBAG HLA*IMP:02 HLA*IMP:03 SNP2HLA
African-American / A 203 94.1 92.9 95.1 88.1
African B 235 88.3 85.1 90.0 77.4
C 203 93.3 92.4 94.6 79.8
DQA1 355 97.5 94.8 96.3 77.6
DQB1 531 85.2 82.8 86.0 63.0
DRB1 550 91.8 89.8 94.9 90.0
DRB3 338 * 95.6 99.0 *
DRB4 337 * 98.2 99.4 *
DRB5 342 99.1 99.4 99.6 *
Asian A 749 86.2 91.5 92.6 88.9
B 852 89.9 86.2 91.6 85.8
C 759 97.8 96.6 97.7 86.7
DPA1 452 99.3 99.1 99.3 91.5
DPB1 452 88.4 89.0 89.3 83.6
DQA1 487 96.6 96.1 97.4 84.8
DQB1 767 86.7 86.0 88.2 72.4
DRB1 845 87.8 86.8 91.2 88.4
DRB3 12 * 87.5 100.0 *
DRB4 11 * 100.0 100.0 *
DRB5 14 100.0 100.0 100.0 *
Europeans A 6,685 97.7 97.6 97.7 96.4
B 7,999 95.8 94.2 95.7 93.7
C 6,642 98.3 98.1 98.2 94.0
DPA1 5,615 99.7 99.7 99.9 97.5
DPB1 5,686 95.0 95.1 95.6 92.5
DQA1 5,899 99.3 98.8 99.3 91.4
DQB1 7,325 98.0 97.1 98.0 88.2
DRB1 7,918 94.1 93.6 95.0 94.2
DRB3 165 * 96.7 98.5 *
DRB4 197 * 97.5 99.2 *
DRB5 217 99.5 99.8 99.5 *
Latino A 217 91.5 92.4 92.4 89.4
B 350 78.3 73.6 78.9 70.7
C 220 96.1 94.5 96.4 90.2
DPB1 26 84.6 86.5 86.5 82.7
DQA1 42 100.0 98.8 98.8 84.5
DQB1 232 91.6 90.5 94.4 81.0
DRB1 339 83.9 82.2 88.8 84.4
DRB3 23 * 93.5 97.8 *
DRB4 11 * 100.0 100.0 *
DRB5 33 100.0 100.0 100.0 *

References

  1. James M. Jackson, Susanna C. Finn, Edward T. Chambers, Jill M. Rathborne, Robert Simon. THE NESSIE NEBULA: CLUSTER FORMATION IN A FILAMENTARY INFRARED DARK CLOUD. ApJ 719, L185–L189 IOP Publishing, 2010. Link

  2. George D. Greenwade. The Comprehensive Tex Archive Network (CTAN). TUGBoat 14, 342–351 (1993).

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