Hi Reddit! EDIT: And that’s all for us from the Swope Team! Thank you for the great questions. Sorry we couldn’t answer every one of them. And thank you for the reddit gold, even if it wasn’t made in a neutron star-neutron star collision. We are Ben Shappee, Maria Drout, Tony Piro, Josh Simon, Ryan Foley, Dave Coulter, and Charlie Kilpatrick, a group of astronomers from the Carnegie Observatories and UC Santa Cruz who were the first people ever to see light from two neutron stars colliding. We call ourselves the Swope Discovery Team because we used a telescope in Chile named after pioneering astronomer Henrietta Swope to find the light from the explosion that happened when the two stars crashed into each other over a hundred million years ago and sent gravitational waves toward Earth. You can read more about our discovery–just announced yesterday–here: https://carnegiescience.edu/node/2250 Or watch a video of us explaining what gravitational waves and neutron stars even are here: https://vimeo.com/238283885 We also took the first spectra of light from the event. Like prisms separate sunlight into the colors of the rainbow, spectra separate the light from a star or other object into its component wavelengths. Studying these spectra can help us answer a longstanding astrophysics mystery about the origin of certain heavy elements including gold and platinum. You can watch a video about our spectra here: https://vimeo.com/238284111 We’ll be back at 11 am ET to answer your questions, ask us anything! Dr. Ben Shappee: I just completed a Hubble, Carnegie-Princeton Fellowship at the Carnegie Observatories and am mere weeks into a faculty position at University of Hawaii’s Institute for Astronomy. I’m a founding member of the ASAS-SN supernova-hunting project. Dr. Maria Drout: I am currently a NASA Hubble Postdoctoral Fellow at the Carnegie Observatories and I also hold a research associate position at the University of Tornoto. I study supernovae and other exotic transients. Dr. Tony Piro: I am a theoretical astrophysicist and the George Ellery Hale Distinguished Scholar in Theoretical Astrophysics at the Carnegie Observatories. I am the P.I. of the Swope Supernova Survey. Dr. Josh Simon: I am a staff scientist at the Carnegie Observatories. I study nearby galaxies, which help me answer questions about dark matter, star formation, and the process of galaxy evolution. Dr. Ryan Foley: I am a a faculty member at UC Santa Cruz. I represented the Swope Team at the LIGO and NSF press conference about the neutron star collision discovery on Monday in Washington, DC. Dr. Charlie Kilpatrick: I am a postdoc at UC Santa Cruz. I specialize in supernovae. Almost Dr. Dave Coulter: I am a second year graduate student at UC Santa Cruz. I am a founding member of the Swope Supernova Survey. EDIT: Here’s our team! https://imgur.com/gallery/8lZyg
With AI becoming mainstream, how will it affect the way we interact with our devices and how we communicate with each other? My name is Rana el Kaliouby, and I’m an Egyptian-American scientist and entrepreneur on a mission to humanize technology. I care deeply about ethics and trust in AI, from considering algorithmic bias to ensuring consent and data privacy. As Co-founder and CEO of Affectiva, an MIT spin-off that builds artificial emotional intelligence (“Emotion AI”), my company uses cutting-edge software that analyzes complex and nuanced emotional and cognitive states from the human face and voice, ultimately engineering empathy. For me, teaching machines to measure and interpret human emotions has the potential to enhance consumer experiences, engage students and personalize their learning, allow doctors and nurses to deliver better care, increase road safety by tracking driver alertness, and enable people with autism to better communicate with their families and peers. I consider myself a role-model for young scientists who are considering careers in technology and entrepreneurship. As a female Muslim scientist who’s one of a handful of women CEOs in the tech industry, I’m a huge advocate for diversity and inclusion—- not just because it is the right thing to do, but because it is the only way we can design and build smart technologies for an increasingly global world. Today, I’m also a co-host on PBS NOVA’s new series “NOVA Wonders,” in which incredible scientists from all walks of life tackle some of the biggest questions about life and the cosmos. I believe that science is the vehicle for innovation, so I’m truly excited to be a part of “NOVA Wonders”—- I especially love how NOVA shows that scientists come in all shapes, colors and sizes, thus providing diverse role-models that aspiring scientists can relate to and be encouraged by. I’m a World Economic Forum (WEF) Young Global Leader and I served on WEF’s Global Future Council on AI and Robotics. I’m also a member of the Partnership on AI, which is concerned with ensuring that AI benefits society and is applied for good. A former research scientist at the MIT Media Lab with a PhD in computer vision and machine learning from the University of Cambridge, I use my voice to advocate for women in tech and for beneficial uses of AI—- I’m often cited in and interviewed by top business and mainstream outlets, including The New Yorker, Wired, Forbes, Fast Company, The Wall Street Journal, The New York Times and TIME Magazine. Check out my TED talk and my Inc. column, and do make sure to watch PBS NOVA’s episode on Can we Build a Brain, which premieres May 16 on PBS! Ask me anything about being a computer scientist, deep learning, building artificial emotional intelligence, the applications of it, ethics in AI or how its like to be a woman leader in tech. Thank you!
Hi Reddit, I’m Elijah Meeks. I wrote D3.js in Action and I just open sourced Semiotic, a data visualization framework focused on information modeling. I used to do data visualization in the digital humanities, including projects like ORBIS, Kindred Britain and the Digital Gazetteer of the Song Dynasty. Now I work at Netflix visualizing user behavior, algorithm performance and just big data more generally. Lately I’ve been pushing for the community to take a critical look at professional data visualization: how we design roles, how data visualization is seen by leadership and how we evaluate data visualization products. Proof of Life Follow me on Twitter Read my pieces on Medium Some examples of my work: My Blocks A visualization of Archer ORBIS - Geographic and Transportation Data Visualization of the Roman Empire A timeline of US Wars EDIT: Okay I came back and responded to a few more things and it was totally worth it.
Hi Reddit, my name is Natalia Trayanova, and I’m a professor of biomedical engineering and medicine at Johns Hopkins University. My lab uses predictive computer simulations to generate personalized virtual hearts of patients that have life-threatening arrhythmias. These first-of-their-kind virtual hearts are already being used in the clinic to assess patient risk of sudden cardiac death and to guide personalized anti-arrhythmia interventions. Simulation-driven engineering has put rockets in space, and airplanes in the sky. We trust engineering advances with our lives, however, when it comes to our own health, things are quite different. Computer simulations are rarely used in medicine. Our vision is to change this – we aim to bring computer simulations to the clinic, to make precise decisions for treatments for heart disease. We believe implementing an engineering data-driven simulation approach will increase the efficacy of diagnostic and clinical procedures for heart rhythm disorders and democratize the delivery of cardiac healthcare. You can learn more about our virtual heart approach in a recent TEDx talk [https://www.youtube.com/watch?v=wSDMPxGGy3A], and in this video describing our pioneering approach [https://youtu.be/bX62KNOfdBs]. We hope our virtual hearts will become a routine tool in the clinic, improving patient outcomes, which would be an unprecedented merging of computational simulation and clinical medicine. It has been extraordinarily fulfilling to have transcended my role as scientist and engineer, to be working directly with physicians helping patients. This is an unexpected and an exhilarating place to be. I look forward to having you #AskMeAnything on April 2nd, 1 PM ET.
Diversity supports the well-being of any healthy and productive ecosystem. The scholarly research enterprise is no different in this regard. Diversity needs to be designed into the research ecosystem and the interactions across the community. We call the community to refocus its efforts on building a vibrant habitat by supporting diversity and inclusivity.
Creating rankings might seem like a vain exercise in belly-button gazing, even more so for people so unlike that kind of things as programmers. However, in this paper we will try to prove how creating city (or province) based on rankings in Spain has led to all kinds of interesting effects, including increased productivity and community building.
Our recently published paper in the ACS Sustainable Chemistry & Engineering journal describes a quantitative assessment tool to evaluate chemicals and chemical processes against the 12 Principles of Green Chemistry, using generally accepted industry practices and readily available data sources. This tool, called DOZN, provides a consistent framework for measuring and communicating what’s “greener” about the products labeled as “greener alternatives” and is robust and flexible enough to encompass a diverse product portfolio, from biology to chemistry to materials science. So, feel free to ask us anything about this tool and how it’s currently being implemented at MilliporeSigma, or how you can apply it in your organization. We’ll be back at 1:00 PM Eastern Time (10 am PT, 6 pm UTC) to answer your questions, ask us anything! Dr. Jane Murray: I am the head of Green Chemistry for the Life Science business of Merck KGaA, Darmstadt, Germany, which operates as MilliporeSigma in the U.S. and Canada. I have a background in chemical research—having completed my Ph.D. at the University of York, where I researched green oxidations of organosulfur compounds using hydrogen peroxide. I am a member of the American Chemical Society’s Green Chemistry Institute, Chemical Manufacturer’s Roundtable, the Royal Society of Chemistry and the American Chemical Society. Dr. Ettigounder “Samy” Ponnusamy: I am the Green Chemistry Fellow with the Life Science business of Merck KGaA, Darmstadt, Germany, which operates as MilliporeSigma in the U.S. and Canada. In this role, I manage and expand new green business opportunities, as well as research and develop greener alternatives—including spearheading the DOZN tool that we’ll be talking about on this AMA. I have more than 30 years of experience managing new product developments—from bench scale through product launch—with many products showing sustained growth over time. I earned my Ph.D. from the University of Madras and am the co-author of 30 related scientific articles and holder/co-holder of seven patents. Edit: We forgot to include the link to the paper: http://pubs.acs.org/doi/pdfplus/10.1021/acssuschemeng.6b02399 Edit 2: We’ll be back in an hour to begin answering but wanted to share a link to the 12 Principles of Green Chemistry that we referred to at the top - https://www.acs.org/content/acs/en/greenchemistry/what-is-green-chemistry/principles/12-principles-of-green-chemistry.html Edit 3: Hi everyone, thank you for all of the questions. We’ll be sticking around until 2:30 EST to answer questions, so keep them coming. If you’re interested in learning more about MilliporeSigma’s program, you can go to www.sigma.com/greener Edit 4: Thank you everyone for the great questions! This was both of our first times on Reddit and we appreciate the informative and engaging discussion - hopefully you did as well. We’re sorry if we weren’t able to get to your question but we hope to be back here sometime soon. If you have time, feel free to take a look at the links we shared above and throughout our answers. If you’d like to see an example of our DOZN scoring for a real product, you can see it here: http://www.sigmaaldrich.com/catalog/product/sigma/a7005 If you have any other feedback or questions, please continue to post. We’ll continue to revisit this thread and may even answer a few more questions. Thank you again!
Hi there, I work in the graphics department at the Financial Times website/newspaper where I have worked for over 22 years and have seen many changes in this industry over my career. My main area of interest is in cartography but you can ask me anything you want with regards to visualising data, telling stories with data, processes, software, working in a newsroom, how I got into data visualisation. Check out these links of previous work China’s polluted skies Air pollution: why London struggles to breathe Japan: the next big quake Sand castles on Jersey shore: property boom defies US flood risk Data visualisation: how the FT newsroom designs maps Global M＆A exceeds $3tn for fourth straight year Apple tests new iPhone price threshold at $999 Germany’s election results in charts and maps Due to the overwhelming response to a few of my recent posts on r/dataisbeautiful I thought it would be a good time to host an AMA Pollution in London 3D animation of pollution in China Animation of flooding caused by Ilisu Dam Proof: https://i.redd.it/dc6ab3noa9o11.jpg
Hi Reddit, We are graduate students and postdocs in Professor Frances Arnold’s research group at Caltech. We use directed evolution, the algorithm for which Frances won the Nobel Prize last week, as a tool to engineer proteins. Directed evolution, like Darwinian evolution, is about “survival of the fittest” by selecting beneficial mutations that enhance a desired function. The key difference is that in directed evolution the person running the experiment chooses which mutations are beneficial – in other words, we choose the definition of “fittest” in “survival of the fittest.” Understanding how a protein’s sequence connects to its structure is challenging (relevant XKCD), and understanding how that structure confers function is another significant challenge. A strength of directed evolution is that one does not need to know a lot about the protein to use it; all one needs is the genetic information (the DNA that encodes the protein of interest) and a way of testing each variant for the function of interest. We don’t need to know exactly how or why the protein is able to catalyze a reaction or understand why a mutation enhances that activity. Proteins have been engineered using directed evolution for myriad uses, from higher stability for use in your laundry detergent to remove stains to producing blockbuster pharmaceutical compounds in place of less environmentally friendly syntheses. Unfortunately Frances is not able to join us for the discussion, but we are happy to answer any questions you have about directed evolution, proteins, Caltech, and beyond! Useful links on directed evolution: “What is directed evolution and why did it win the chemistry Nobel prize?” from Chemistry World C&EN Online explanation of directed evolution and phage display Frances discussing the Nobel Prize on NPR’s Science Friday TEDxUSC talk by Frances: “Sex, Evolution, and Innovation” Learn more about the Arnold Group: http://fhalab.caltech.edu/ Follow Dr. Arnold on Twitter: https://twitter.com/francesarnold Our discussion panel guests today are: Anders Knight ( /u/AndersKnight ): Anders is a fourth-year bioengineering graduate student in the Arnold lab. He works on engineering heme proteins to do carbene transfer reactions not found in nature. An open-access paper on these kinds of reactions is available here. Kari Hernandez ( /u/Kari_Hernandez ): Kari is in the 4th year of her Ph.D. and received her B.S. in chemical engineering from the University of Arizona. Her work focuses on making useful molecules by evolving heme proteins to do non-natural reactions. Jennifer Kan ( /u/JennyKan ): Jenny is a postdoc in Frances Arnold’s lab at Caltech. Her favourite thing to do is to teach proteins to make cool bonds. Twitter: @sbjennykan Tina Boville ( /u/TinaBoville ): Tina is a postdoc in the Arnold lab evolving enzymes to make chemical building blocks called noncanonical amino acids. She is very interested in green chemistry and lab sustainability and is a fellow at the Resnick Institute. Patrick Almhjell ( /u/PatrickAlmhjell ): Patrick is a second-year graduate student in the Biochemistry and Molecular Biophysics program at Caltech, working on the same project as /u/TinaBoville. Patrick loves chemistry but not the chemistry lab, so he appreciates being able to use enzymes in water instead. An open-access review on noncanonical amino acid synthesis is available here. Kevin Yang ( /u/KevinKYang ): Kevin is a 5th year PhD student in Frances Arnold’s lab. His research focuses on using machine learning to accelerate directed evolution. Read his open-access paper on using machine learning in protein engineering. Zach Wu ( /u/zvxywu ): Zach is a 4th year graduate student in Chemical Engineering. His research focuses on developing methods for engineering proteins efficiently and understanding the sequence function relationship. Our guests will begin answering questions starting at 1:00PM PST.
Hi everyone, happy to be here! Hyperhidrosis is a common condition, approx 3% of people deal with excessive sweating from their armpits, palms or soles of feet. It can be debilitating, the sweating is often heavy and uncontrollable, causing people to really struggle in social and work situations. The good news is that hyperhidrosis is highly treatable. At the Columbia Hyperhidrosis Center, our team of thoracic surgeons and dermatologists developed a multidisciplinary approach to the management of hyperhidrosis. While surgery is extremely effective at eliminating hyperhidrosis, there may be some unavoidable side effects, so we believe non-surgical options should be tried first. Here’s a little bit more about me and an interview about hyperhidrosis. Here’s my proof Edit: Thank you Reddit, I’ve enjoyed answering your questions. I’m signing off for now, and will try to check back in later today. Happy holidays!
Hi reddit, I’m Hilary Lawson - post-realist philosopher, director of the Institute of Art and Ideas and founder of the world’s largest philosophy and music festival HowTheLightGetsIn. Born and raised in Bristol, England, I was awarded a scholarship to study PPE at Balliol College Oxford . As a post-graduate I came to see paradoxes of self-reference as the central philosophical issue and began a DPhil on The Reflexivity of Discourse. This later became the basis for my first philosophical book Reflexivity: The Post-Modern Predicament. Alongside my more philosophical writing, I also pursued a media career following my studies. Within a few years I had created my own prime time television series ‘Where There’s Life’ with a weekly UK audience in excess of ten million. In 1982, I went on to co-author a book based on the series and was appointed Editor of Programmes and later Deputy Chief Executive at the television station TV-am. Meanwhile I continued to develop my philosophical thinking and had initial sketches of the theory later to become Closure. In 1985 I wrote Reflexivity: The Post-Modern Predicament as part of a series on modern European thought. In the book, I argued that the paradoxes of self-reference are central to philosophy and drive the writings of Nietzsche, Heidegger and Derrida. In the late 1980s I founded the production company TVF Media which made documentary and current affairs programming, including Channel 4’s flagship international current affairs programme, The World This Week. I was editor of the programme, which ran weekly between 1987 and 1991. The programme predicted the fall of the Berlin Wall, the war in Yugoslavia and the Iraqi invasion of Kuwait, amongst its other laudable achievements. In the 1990s, I focused on writing Closure. It took a decade to complete and was published in 2001. The book has been described as the first non-realist metaphysics. Having begun my philosophical career as a proponent of postmodernism, latterly I became a critic arguing for the necessity of an overall framework and the need to move on from a focus on language. Closure proposes that the human condition is to find ourselves on the cusp of openness and closure. The world is open and we, along with other living organisms, are able to apprehend and make sense of it through the process of closure. I would define closure as the holding of that which is different as one and the same. Human experience is seen to be the result of successive layers of closure, which I consider to be preliminary, sensory and inter-sensory closure. The highest level of closure, inter-sensory closure realises language and thought. The theory shifts the focus of philosophy away from language and towards an exploration of the relationship between openness and closure. An important element of the theory of closure is its own self-referential character. I founded the Institute of Art and Ideas in 2008 with the aim of making ideas and philosophy a central part of cultural life. Our website IAI.tv, which posts to the sub, was launched in 2011. We then moved to publishing articles in 2013 and free philosophy courses on IAI Academy in 2014. Links of Interest: Tickets and lineup for HowTheLightGetsIn 2018 can be found here - discounts available for students and U25s. Routledge has partnered with the IAI to offer a generous 20% off all their philosophy books and a free giveaway each month. Click here for details. After the End of Truth: A debate with Hannah Dawson (KCL) and John Searle (Berkeley) on objective truth and alternative facts What Machines Can’t Do | Hilary Lawson in debate with David Chalmers (NYU) and cognitive scientist and sex robot expert Kate Devlin (Goldsmiths) on the question of machine minds After Relativism: A debate on the pitfalls of relativism and potential solutions with Simon Blackburn and Michela Massimi
Hi Reddit, my name is Chris Ruff [https://www.hopkinsmedicine.org/profiles/results/directory/profile/0000031/christopher-ruff], and I’m an anatomist and biological anthropologist at the Johns Hopkins University School of Medicine. During my 35 years of teaching anatomy, I’ve seen many changes in how we introduce students to this subject. Anatomy forms the foundation for much of medicine, but can be difficult to learn, so finding the best ways to communicate that information is important. Dissection of cadavers has always been a key part of anatomical training, because of the realism and experience with the actual body that it involves. However, increasingly we also use computer software to reinforce or review anatomical structures or concepts. Recently, we have developed a new product that makes learning muscles and bones fun and interactive. It’s designed for both medical professionals and anatomy neophytes. [https://www.hopkinsmedicine.org/news/articles/anatomy-app-offers-interactive-learning-from-johns-hopkins-expert] I’ll be back at 1 pm ET today to answer your questions.