Hey Reddit! We’re a group of scientists and engineers from the Chan Zuckerberg Initiative – a philanthropic organization founded by Mark Zuckerberg and Priscilla Chan. We’re working to help cure, prevent, or manage all diseases by the end of the century. One of the ways we’re doing that is by helping to build a Human Cell Atlas – a world-wide effort to map all of the cells in the human body – think the human genome project, but for cells (of which there are 30 trillion) rather than genes (of which there are 20,000 or so). Our big-picture goal is to support a fully open project in which scientists can share their knowledge to assemble a parts list of the cells in the healthy human body, and we’re looking for people who are interested in collaborating to develop new computational tools in support of this effort. We’d love to talk to you about this and anything else related to our work on the Human Cell Atlas. Here is a photo of the team. We’ll be back at between 10am - 12pm PT to answer your questions – ask us anything! Cori Bargmann, PhD – Torsten N. Wiesel Professor and head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior at the Rockefeller University in New York. President of Science at CZI. Jeremy Freeman, PhD — Neuroscientist, and Manager of Computational Biology at CZI Deep Ganguli, PhD – Computational Biologist Katja Brose, PhD – Neuroscientist, Science Program Officer Bruce Martin – Director of Engineering Andrey Kislyuk, PhD – Software Engineer (PS – If you want to learn more about the Human Cell Atlas, check out this recent podcast from JAMA.) EDIT – Hey folks, we’re signing off for now, but will check back now and again to answer additional questions. Thanks to everyone who participated!
Relativization: The act of constructing a physical model which obeys the Einstein equivalence principle. This paper corrects and extends the initial results regarding black hole thermodynamics revealed in the preceding paper. In the process of correcting and extending those initial upper bounds on the intensity of Hawking radiation from a micro black hole, I will Quantitative find much more. It will be demonstrated that a Schrodinger like equation derived in the previous papers once solved in position basis with the proper boundary conditions will give a model which works on any imaginable length scale. This will be worked out analytically with accuracy precision by the aid of
Medical students and residents often seek advice on a variety of topics from more senior physicians. Herein, I share the collected wisdom of 40 practicing physicians on topics of general interest to undergraduate and graduate medical trainees. Much of this advice is applicable to physicians already in practice.
Creating rankings might seem like a vain exercise in belly-button gazing, even more so for people so unlike that kind of things as programmers. However, in this paper we will try to prove how creating city (or province) based on rankings in Spain has led to all kinds of interesting effects, including increased productivity and community building.
One of the ways that early career researchers can effect change in the academic research system is to make their voices heard, particularly when their input is solicited. Two agencies are soliciting such input until early March 2015: a survey responding to the Federation of American Societies for Experimental Biology (FASEB) Report “Sustaining Discovery in Biological and Medical Sciences: A Discussion Framework”; and a Request for Information on the “Emeritus Award for Senior Researchers” from the National Institutes of Health (NIH). Here we present a call to the scientific community to contribute to the discussions; provide resources that can allow researchers to read further and make informed comments on the proposals; and discuss the proposals in the hope of provoking further debate.
Currently NIH has put out a request for information (RFI) to “Optimizing Funding Policies and Other Strategies to Improve the Impact and Sustainability of Biomedical Research”. Here I open my response (unabridged version) submitted to this RFI. With the hope and intention of stimulating the scientific community to submit a response of their own as well as criticize, debate and use as resource, the points in this response.