loading page

ICD in Cardiac Sarcoidosis: Variables associated with appropriate therapy, inappropriate therapy, and device complications
  • Sebastian Mactaggart,
  • Raheel Ahmed
Sebastian Mactaggart
Northumbria Healthcare NHS Foundation Trust

Corresponding Author:[email protected]

Author Profile
Raheel Ahmed
Royal Brompton Hospital
Author Profile

Abstract

Introduction: Those with cardiac sarcoidosis (CS) are at risk of sudden cardiac death (SCD), which may be prevented using an implantable cardioverter defibrillator (ICD). There is limited data available that follows the post-procedural outcomes of patients with cardiac sarcoidosis (CS) who have had an ICD implanted. Areas Covered: This review will highlight studies that focus on both appropriate and inappropriate therapies in those with an ICD, as well as device complications in this group. There were several variables inclusive of age, gender, ventricular characteristics and findings on cardiac imaging that were investigated and discussed as influencing factors in predicting appropriate and inappropriate therapies. Conclusions: Adverse events in those with an ICD and CS were minimally reported in the literature. Individuals diagnosed with CS are at high risk of ventricular arrhythmia, with comparable rates of appropriate therapy but higher incidence of side effects and inappropriate therapy. The younger average age of CS patients in comparison to other ICD cohorts warrants the need for further, large-scale, prospective trials with periodic interim follow-ups focused on those with this condition.