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Laryngeal chondrosarcoma associated to cervical lymph node metastasis of papillary thyroid carcinoma. A systematic review.
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  • OSCAR ALVAREZ-CALDERON-IGLESIAS,
  • Mario Pérez Sayáns,
  • Rafael Hurtado-Ruzza,
  • Celia Lendoiro-Otero,
  • Clara Gonzalez Nuñez,
  • Alejandro Lorenzo-Pouso,
  • Manuel Blanco-Labrador
OSCAR ALVAREZ-CALDERON-IGLESIAS
Ourense Hospital

Corresponding Author:[email protected]

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Mario Pérez Sayáns
University of Santiago de Compostela
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Rafael Hurtado-Ruzza
Ourense Hospital
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Celia Lendoiro-Otero
Ourense Hospital
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Clara Gonzalez Nuñez
Ourense Hospital
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Alejandro Lorenzo-Pouso
Universidade de Santiago de Compostela
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Manuel Blanco-Labrador
Ourense Hospital
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Abstract

Objective: Laryngeal chondrosarcomas (LCS) are rare tumors with good prognosis. The coexistence of LCS and cervical metastasis of papillary thyroid carcinoma (PTC) is scarce. The main objective of this research was to review clinical aspects and management of LCS . A secondary objective was to find the coexistence of LCS with cervical Lymph node metastasis of papillary thyroid carcinoma (LNMPTC) in all the cases included in the search. Design: A Systematic Review was performed using PubMed, Web of Science, Scopus and Embase databases. We followed PRISMA guidelines and the PECOS method to characterize different aspects of LCS. Reports of laryngeal chondrosarcoma were included and information about symptoms, imaging technique, treatment modality, histopathological diagnosis, location, tumor size, recurrence, and follow-up data was extracted. Results: Three hundred and eighty one cases of LCS were included. The average age was 61.1 years. The most common symptoms were dyspnea and hoarseness. Cricoid cartilage was the most usual location. Survival was affected by histologic differentiation, tumoral location and surgical technique. We identified the coexistence of LCS and PTC in 2 cases. In none of them the authors reported LNMPTC. Conclusion: The coexistence of LCS and PTC is rare. LCS is a tumor with good prognosis. Different approaches are described in literature.