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Comparison of SARS-CoV-2 VOC 202012/01 (UK variant) and D614G variant transmission by different routes in Syrian hamsters
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  • Sreelekshmy Mohandas,
  • Pragya Yadav,
  • Dimpal Nyayanit,
  • Anita Shete,
  • Prasad Sarkale,
  • Supriya Hundekar,
  • Sanjay Kumar,
  • Kavita Lole
Sreelekshmy Mohandas
National Institute of Virology
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Pragya Yadav
National Institute of Virology

Corresponding Author:[email protected]

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Dimpal Nyayanit
National Institute of Virology
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Anita Shete
National Institute of Virology
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Prasad Sarkale
National Institute of Virology
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Supriya Hundekar
National Institute of Virology
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Sanjay Kumar
Command Hospital Pune
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Kavita Lole
National Institute of Virology
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Abstract

Many SARS-CoV-2 variants of concern has been reported recently which were linked to increased transmission. In our earlier study on virus shedding using VOC 202012/01(UK variant) and D614G variant in hamster model, we observed significantly higher viral RNA shedding through nasal wash in case of UK variant. Here, we have compared the transmission of both the UK and D614G variant by various routes in Syrian hamsters to understand the transmission efficiency of the variant. The study demonstrated comparable transmission efficiency of both UK and D614G variants of SARS-CoV-2 in Syrian hamsters.