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Cardiovascular risk factors predict who should have echocardiographic evaluation in long COVID
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  • Leonardo Tamariz,
  • Mathew Ryan,
  • George Marzouka R,
  • Elizabeth Bast,
  • Nancy Klimas,
  • Ana Palacio
Leonardo Tamariz
University of Miami School of Medicine

Corresponding Author:[email protected]

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Mathew Ryan
University of Miami School of Medicine
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George Marzouka R
University of Miami School of Medicine
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Elizabeth Bast
VA Miami Healthcare System
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Nancy Klimas
Nova Southeastern University
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Ana Palacio
University of Miami School of Medicine
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Background: The need for echocardiograms among patients with long COVID is debatable. Our aim was to evaluate the prevalence of left ventricular (LV) dysfunction and identify predictors. Methods: We conducted a cross-sectional study and included all consecutive patients enrolled in our post-COVID clinic. We included patients who had an echocardiogram and had no previous known heart disease. We defined LV dysfunction as a low ejection fraction or grade II to grade III diastolic dysfunction on an echocardiogram with evidence of elevated filling pressures. We calculated the prevalence of heart disease and predictors of heart disease using logistic regression. Results: We included 217 post-COVID patients enrolled in the clinic. The prevalence of LV dysfunction is 24%;95% CI 18-30. Predictors of heart disease include older age and a previous history of hypertension and diabetes or having a intermediate or high ASCVD score. Patients with low ASCVD score did not have low ejection fraction on the screening echocardiograms. Conclusion: Our study found a considerable number of patients with LV dysfunction. Older patients with cardiovascular risk factors are at risk of long COVID associated heart disease.
22 Aug 2023Submitted to Echocardiography
23 Aug 2023Submission Checks Completed
23 Aug 2023Assigned to Editor
07 Sep 2023Reviewer(s) Assigned
27 Sep 2023Review(s) Completed, Editorial Evaluation Pending
28 Sep 2023Editorial Decision: Revise Major
03 Nov 20231st Revision Received
09 Nov 2023Submission Checks Completed
09 Nov 2023Assigned to Editor
09 Nov 2023Reviewer(s) Assigned
20 Nov 2023Review(s) Completed, Editorial Evaluation Pending