An overview of experimental methodologies for bioactive glass-coated Ti
implants assessment in orthopedic and dental applications
- XinYue Lu,
- Yu Ru Li,
- XinRu Zheng,
- XiaoYu Geng,
- XuanYi Wang,
- Dan Yang,
- Heng Bo Jiang
XinYue Lu
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Corresponding Author:[email protected]
Author ProfileYu Ru Li
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Author ProfileXinRu Zheng
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Author ProfileXiaoYu Geng
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Author ProfileXuanYi Wang
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Author ProfileDan Yang
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Author ProfileHeng Bo Jiang
The CONVERSATIONALIST club School of Stomatology Shandong First Medical University & Shandong Academy of Medical Sciences Jinan Shandong 250117 China
Author ProfileAbstract
Bioactive glass, as an ideal biomaterial, is not suitable for
load-bearing parts because of its high brittleness and has been applied
for surface modification to manufacture composite materials. Titanium
alloy is bio-inert and prone to loosening, which leads to implant
failure and infection after implantology. Applying bioactive glass to
titanium and its alloys in the form of coating combines titanium metal's
superior mechanical properties and bioglass's good biological
properties. In this review, the authors searched and screened four
databases, including Web of Science, PubMed, Embase, and Scopus, for
articles published since 2013, finally, 49 articles were included to
investigate the biological properties of bioactive glass coatings on
titanium and its alloys. From the perspective of methodology, this
review aims to summarize the methodologies performed for detecting the
biological properties including biocompatibility and bioactivity of
coatings were also concluded, covering the experimental process and
principle of the included studies, therefore, providing learning
materials for new researchers in material science and biotechnology.