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Giant Coronary Aneurysms in an Infant: Dilemma of MIS-C
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  • Alexandra Drury,
  • Kelsey Wold,
  • Steven Healan,
  • Ashish Garg
Alexandra Drury
Washington State University Elson S Floyd College of Medicine

Corresponding Author:alexandra.drury@wsu.edu

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Kelsey Wold
Kadlec Regional Medical Center
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Steven Healan
Providence Sacred Heart Medical Center
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Ashish Garg
Washington State University Elson S Floyd College of Medicine
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COVID-19 related MIS-C (Multisystem inflammatory syndrome in children) can present with cardiovascular complications like shock, arrhythmias, pericardial effusion, and coronary artery dilatation. The majority of MIS-C associated coronary artery abnormalities are dilation or small aneurysms which are transient and resolve in a few weeks[[1, 2]](#ref-0001). We present here a case of a 3-month-old child who was noted to have giant aneurysms of her coronary arteries (LAD and RCA) twenty-six days after testing positive for COVID-19. She was treated with IVIG, infliximab, and glucocorticoids along with aspirin, clopidogrel and enoxaparin. She did not show any signs of coronary ischemia or cardiac dysfunction but continued to have persistent giant coronary artery aneurysms involving the LAD (z-score ~35) and RCA (z-score ~30) [Fig. 1]. This study emphasizes the importance of early detection and aggressive management of MIS-C to prevent potentially life-threatening consequences.
10 Mar 2022Submitted to Echocardiography
10 Mar 2022Submission Checks Completed
10 Mar 2022Assigned to Editor
13 Mar 2022Reviewer(s) Assigned
06 Apr 2022Review(s) Completed, Editorial Evaluation Pending
10 Apr 2022Editorial Decision: Revise Minor
28 Apr 20221st Revision Received
28 Apr 2022Submission Checks Completed
28 Apr 2022Assigned to Editor
28 Apr 2022Reviewer(s) Assigned
30 May 2022Review(s) Completed, Editorial Evaluation Pending
06 Jun 2022Editorial Decision: Accept
Jul 2022Published in Echocardiography volume 39 issue 7 on pages 950-953. 10.1111/echo.15408