loading page

Deep vein thrombosis and pulmonary embolism in pediatric COVID-19
  • +8
  • Loukia Ioannidou,
  • Athina Dettoraki ,
  • Maria Noni,
  • Dimitra Koukou,
  • Aiketarini Michalopoulou,
  • Zoey Kapsimalli,
  • Evanthia Botsa,
  • Athanasios Michos,
  • Vana Spoulou,
  • Helen Pergantou,
  • Christina Kanaka-Gantenbein
Loukia Ioannidou
Agia Sofia Children's Hospital
Author Profile
Athina Dettoraki
Agia Sofia Children's Hospital
Author Profile
Maria Noni
National and Kapodistrian University of Athens
Author Profile
Dimitra Koukou
Agia Sofia Children's Hospital
Author Profile
Aiketarini Michalopoulou
Agia Sofia Children's Hospital
Author Profile
Zoey Kapsimalli
Agia Sofia Children's Hospital
Author Profile
Evanthia Botsa
National and Kapodistrian University of Athens - Faculty of Medicine
Author Profile
Athanasios Michos
University of Athens
Author Profile
Vana Spoulou
National and Kapodistrian University of Athens
Author Profile
Helen Pergantou
Agia Sofia Children's Hospital
Author Profile
Christina Kanaka-Gantenbein
National and Kapodistrian University of Athens - Faculty of Medicine
Author Profile

Abstract

Thrombotic complications of SARS-CoV-2 have been increasingly recognized as an important component of COVID-19 in adults; however, they have been less evident in children. We report a case of a teenager with positive SARS‐CoV‐2 RT–PCR and underlying prothrombotic risk factors, including aromatase inhibitor therapy, who developed deep vein thrombosis resulting in pulmonary embolism. Laboratory tests revealed deranged coagulation parameters (high D-dimers and Factor VIII and low antithrombin). The patient required intensive care and was managed with anticoagulants, dexamethasone and antithrombin concentrate. Clinical condition and hemostatic profile gradually improved. A review of the available literature for similar cases is presented.
22 Sep 2021Submitted to Pediatric Pulmonology
24 Sep 2021Submission Checks Completed
24 Sep 2021Assigned to Editor
26 Sep 2021Reviewer(s) Assigned
04 Nov 2021Review(s) Completed, Editorial Evaluation Pending
08 Nov 2021Editorial Decision: Revise Major
04 Feb 20221st Revision Received
07 Feb 2022Assigned to Editor
07 Feb 2022Submission Checks Completed
07 Feb 2022Reviewer(s) Assigned
24 Feb 2022Review(s) Completed, Editorial Evaluation Pending
03 Mar 2022Editorial Decision: Revise Minor
04 Apr 20222nd Revision Received
09 Apr 2022Submission Checks Completed
09 Apr 2022Assigned to Editor
09 Apr 2022Reviewer(s) Assigned
12 Apr 2022Review(s) Completed, Editorial Evaluation Pending
15 Apr 2022Editorial Decision: Accept