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The Relationship between CRP at Admission and Thorax CT Findings in Patients Diagnosed with COVID-19
  • Engin Beydoğan,
  • Pınar Yürük Atasoy
Engin Beydoğan
Van Training and Research Hospital
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Pınar Yürük Atasoy
Van Training and Research Hospital
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Abstract

Introduction: The current study aims to evaluate the relationship between C-reactive protein (CRP) levels, thorax CT findings and CT-SS in patients presenting to the emergency department with COVID-19. Methods: Patients diagnosed with COVID-19 by nasopharyngeal rt-PCR (+) in the emergency department were included in the study. In addition to the CRP, ferritin and D-dimer examinations of patients at admission, thorax CT involvement findings and CT-SS results were recorded. The relationship of CRP value with CT-SS and clinical outcome was evaluated. Results: A total of 974 COVID-19 patients, 572 males (58.7%) and 402 females (41.3%), with a mean age of 59.64±17.34 years, were included in the study. The CRP values of the patients who needed intensive care and needed respiratory support were also significantly higher at admission (95.1 mg/dL vs. 31.05 mg/dL) (p<0.001). The CRP values of the patients who developed any complications during the treatment of COVID-19 were higher (79.9 mg/dL vs. 41.85 mg/dL) (p<0.001). In the case of CRP >124.5, a thorax CT density score 7.35 times higher was determined to be severe. In addition, it was determined that there was a 9.09-fold increase in the incidence of negative imaging findings in terms of COVID-19 in cases where the CRP value was <12.5 mg/dL. Conclusion: The CRP levels of COVID-19 patients measured upon admission to the emergency room are correlated with the severity of lung involvement and are an important predictor of clinical outcomes.
17 Aug 2021Submitted to International Journal of Clinical Practice
19 Aug 2021Assigned to Editor
19 Aug 2021Submission Checks Completed
06 Sep 2021Reviewer(s) Assigned
04 Oct 2021Review(s) Completed, Editorial Evaluation Pending
04 Oct 2021Editorial Decision: Accept
05 Nov 2021Published in International Journal of Clinical Practice. 10.1111/ijcp.14962