COVID-19 with rapid progression to hypoxemia likely due to imbalance
between ventilation and blood flow: A case report
- Nobuyuki Koriyama
, - Akihiro Moriuchi,
- Kensaku Higashi,
- Tetsuro Kataoka,
- Takuro Arimizu,
- Go Takaguchi,
- Hideki Matsuoka,
- Maki Otsuka
Akihiro Moriuchi
National Hospital Organisation Kagoshima Medical Center
Author ProfileKensaku Higashi
National Hospital Organisation Kagoshima Medical Center
Author ProfileTetsuro Kataoka
National Hospital Organisation Kagoshima Medical Center
Author ProfileTakuro Arimizu
National Hospital Organisation Kagoshima Medical Center
Author ProfileGo Takaguchi
National Hospital Organisation Kagoshima Medical Center
Author ProfileHideki Matsuoka
National Hospital Organisation Kagoshima Medical Center
Author ProfileMaki Otsuka
National Hospital Organisation Kagoshima Medical Center
Author ProfileAbstract
We experienced a case of COVID-19 with hypoxia, which was presumed to be
due to the development of ventilation and blood flow imbalance by
pulmonary intravascular coagulopathy or hypoxic pulmonary
vasoconstriction. Early, short-term combination therapy with remdesivir,
nafamostat mesilate and low-dose dexamethasone was extremely effective.Jan 2022Published in Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine volume 16 on pages 117954842110732. 10.1177/11795484211073273 
