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COVID-19 with rapid progression to hypoxemia likely due to imbalance between ventilation and blood flow: A case report
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  • Nobuyuki Koriyama,
  • Akihiro Moriuchi,
  • Kensaku Higashi,
  • Tetsuro Kataoka,
  • Takuro Arimizu,
  • Go Takaguchi,
  • Hideki Matsuoka,
  • Maki Otsuka
Nobuyuki Koriyama
National Hospital Organisation Kagoshima Medical Center
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Akihiro Moriuchi
National Hospital Organisation Kagoshima Medical Center
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Kensaku Higashi
National Hospital Organisation Kagoshima Medical Center
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Tetsuro Kataoka
National Hospital Organisation Kagoshima Medical Center
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Takuro Arimizu
National Hospital Organisation Kagoshima Medical Center
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Go Takaguchi
National Hospital Organisation Kagoshima Medical Center
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Hideki Matsuoka
National Hospital Organisation Kagoshima Medical Center
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Maki Otsuka
National Hospital Organisation Kagoshima Medical Center
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Abstract

We experienced a case of COVID-19 with hypoxia, which was presumed to be due to the development of ventilation and blood flow imbalance by pulmonary intravascular coagulopathy or hypoxic pulmonary vasoconstriction. Early, short-term combination therapy with remdesivir, nafamostat mesilate and low-dose dexamethasone was extremely effective.