Elexacaftor/tezacaftor/ivacaftor in an individual with cystic fibrosis
caused by a N1303K CFTR variant and infected with Mycobacterium
This report describes a case of a 15-year-old male with cystic fibrosis
caused by N1303K and Q493X cystic fibrosis transmembrane conductance
regulator (CFTR) protein variants. In this case, CFTR modulators
including tezacaftor/ivacaftor and subsequently
elexacaftor/tezacaftor/ivacaftor were utilized and resulted in clinical
stability and improvement.