Introduction: Anaphylaxis is a potentially life threatening allergic
reaction that is rapid in onset and multisystemic in nature.
Distribution of anaphylaxis tends to fluctuate based on age, gender,
race, geographical residence and socioeconomic status of the involved
subjects. Diagnosis of anaphylaxis in children is generally
underestimated particularly in developing countries, and when diagnosed,
proper management is occasionally lacking. Aim of the study: to evaluate
the frequency and pattern of anaphylaxis and mistakes in diagnosis and
treatment among a group of Egyptian children and adolescents. Subjects
and methods: This observational study was conducted over 6 months
duration, from 1st of September 2019 to the end of February 2020, in
Children’s hospital, Ain Shams University, Cairo, Egypt, on children
presenting to emergency department (ED). Anaphylaxis frequency,
presentation, triggers, diagnosis, management and long term follow up
were assessed. Results: frequency rate of anaphylaxis among children and
adolescents was 0.43% (80/18816) over a year. Sixty percent of patients
were infants. Biphasic reactions were reported in 11.3% of patients.
The commonest trigger was food (22.5%) followed by medications (8.8%).
Epinephrine was given to all patients, in proper dosage and method in
most occasions (78.7%). Long term management and follow up appointment
were deficient. In conclusion: Anaphylaxis in children was relatively
high, with food being the most common trigger. Diagnosis and early
management of anaphylaxis was satisfactory, however, long term
management and follow up were defective.