Background: Coronavirus (COVID-19) pandemic has brought adjustments to ophthalmology clinics, especially vitreoretinal clinics where examinations and procedures are performed in close contacts. Screening and surgery prioritization policy are essential to maintain safety for medical personnel and patients. Aim: To present implementation of screening and surgery prioritization policy in a tertiary ophthalmology referral center in Indonesia. Methods: Safety protocol was implemented in Kirana Eye Center, Cipto Mangunkusumo Hospital, Jakarta, Indonesia from April 2020 to prevent COVID-19 spread. Initial screening consisted of temperature checking, hand hygiene, and questionnaire of COVID-19 signs and symptoms, was performed to patients and caregivers. Those with sight-threatening emergencies were prioritized. Sight-threatening surgical cases were also prioritized. Records of patients in vitreoretinal clinic and operating room were taken on April 2020. Data on diagnosis and procedures was analysed. Results and discussion: There were drastic declines in the number of patients allowed entry to the clinic and patients underwent surgery. There was approximately 80% decrease of patients coming into the clinic with total of 314 patients during March 2020. Most of these patients were pre-existing patients followed up after surgery, patients with diabetic retinopathy and retinal detachment (RD). Most cases managed surgically were RD. Most carried out procedure was vitrectomy, endolaser, and silicone oil tamponade. Conclusion: Our protocol of safety has been successful in reducing patients coming in to our facility but still manage to treat those with sight-threatening conditions. Our protocol may be a model for developing countries. Keywords: COVID-19, vitreoretinal clinic, public health, health policy Word count: 248