PLOS Science Wednesday: Hi Reddit, we’re Ben and Liz and we found age
substantially impacts cognitive processing, indicating our method is
useful for examining individual age-related differences in brain
function – Ask Us Anything!
Abstract
Hey Reddit, I’m Liz Davison, a graduate student at Princeton University
in the Mechanical and Aerospace Engineering Department. My research
centers on development and application of analytical and computational
methods from network science and engineering to study complex dynamical
systems, including the human brain. And I’m Ben Turner, and I’m a
postdoctoral researcher in cognitive neuroscience at the University of
California, Santa Barbara. My research focuses on using functional
magnetic resonance imaging to better understand human memory. We
recently published a paper titled “Individual Differences in Dynamic
Functional Brain Connectivity Structure Across the Lifespan” in PLOS
Computational Biology. This paper applied a method for characterizing
how connections between brain regions change together over time (see our
earlier article published in PLOS Computational Biology to a group of
people including young and older adults. Using different methods, other
researchers have shown that the neural activity in parts of the brain
that belong to the same “network” in young adults tends to become less
similar by older adulthood. Our results extend this previous result by
showing that when brain regions are put in groups based on how their
connections change together over time, older adults have a larger number
of groups relative to young adults, indicating less-cohesive changes in
connectivity. We’ll be here at 1pm to answer your questions – Ask Us
Anything! And feel free to follow Ben on Twitter @neurobot01.