Ataxia-telangiectasia (A-T) is a multi-system disorder, resulted from the mutation in the ATM gene. Its mortality is largely related to some other disorders. Therefore, the management of its complications significantly improves patient quality of life. We studied a pediatric patient with A-T who one of his relatives had A-T.

We present a patient with a rare ectopic retrosternal goitre that underwent a right hemithyroidectomy via an open cervical and video assisted thoracoscopic surgery (VATS). This case report reviews the work-up and radiological features of retrosternal goitre(RSG) and provides an update on the management of RSG.

Soft tissue, bone, and teeth reconstruction is a challenge in patients with maxillary defects due to surgical resections. This article presents a 21-year-old male patient with a history of hemimaxillectomy . Secondary reconstruction was performed using buccal fat pad flap, free iliac crest bone graft, and dental implants

This case series study was performed on 19 patients with facial papule The patients were treated with oral isotretinoin 20 mg for 6 months. Oral isotertinoin was an effective and safe treatment in patients with facial LPP. There were some patients with only facial involvement without FFA or scalp LPP

Osteogenesis Imperfecta is a genetic disorder of connective tissue leading to bone fragility. Diagnosis of this condition can be considered during pregnancy, at birth or during childhood. Early onset forms are severe with high mortality rate. We report two cases during neonatal period in Cameroon.

We present a case of non-leukemic (lymphomatous) variant of HTLV-1 associated adult T-cell leukemia/lymphoma in a young woman. Tumor demonstrated strong and diffuse CD30 and PD-1 expression which is very unusual finding in this entity. Very good clinical response was obtained with brentuximab-containing treatment regimen.

Granulocyte-colony stimulating factor (G-CSF)-producing uterine cervical cancer (UCC) is a rare aggressive disease. We report a case of G-CSF-producing UCC treated with chemoradiotherapy. Target-capture sequencing results indicate that G-CSF-producing UCC is genetically distinct from other UCCs, warranting further research to establish specific treatment strategies.

Bosutinib is a tyrosine kinase inhibitor (TKI) approved for the management of chronic myeloid leukemia (CML). TKIs are associated with pulmonary complications but are rarely described with bosutinib. Here, we report the first description of bosutinib-induced interstitial lung disease and pleural effusion, which resolved after the discontinuation of bosutinib.

Various causes of Recurrent Acute pancreatitis have been identified in the past. This report presents a novel case of “recurrent” acute pancreatitis in the setting of superior mesenteric artery syndrome (SMAS). Thus, highlighting SMAS as a rare yet possible cause of recurrent pancreatitis facilitating early diagnosis and prompt treatment.

Drug reaction with eosinophilia and systemic symptoms is a quite unusual condition related to drug reaction. A case report of sulfasalazine-induced liver failure is described. The patient was submitted to liver transplantation. Liver transplantation is an option when DRESS is associated with acute liver failure, but the prognosis remains poor.

Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis due to various pathologies. Its prevalence ranges upto 10% and can present in different clinical picture to challenge a clinician.

The occurrence of hepatoblastoma is infrequent in children older than 5 years. Therefore, clinicians need to consider hepatoblastoma even in school-aged children or adolescents.

A 70-year-old male presented with a neglected slow growing anal wart for many years with bleeding.A deep core biopsy of the tumor confirmed a high-grade squamous intraepithelial lesion and carcinoma in situ.

Bones, lymph nodes, lungs, or liver, are the common metastatic sites for prostate cancer. However, prostate adenocarcinoma metastasis to the mandible is very rare. In this case report we present a case of a 64-year-old man with poorly differentiated prostate cancer and metastasis to the mandible.

Stab wounds are commonly seen in the emergency room of community hospitals especially in developing countries. The uniqueness of the case to be reported here was that the patient walked in the ER retaining the inflicting weapon in the wound over his back.

Naso-pharyngeal discharge as the first symptom of COVID-19 infection is presented in two cases . Appropriate diagnosis and isolation of the patients who may be at risk for covid-19 such as these cases help reduce further transmission.

An association has been reported between BP and DPP-4 inhibitors. We report three cases of DPP-4 inhibitor-associated BP, with an unfavorable course in 2 patients despite discontinuation of these drugs. Therefore, clinicians should pay close attention to the clinical course of DPP-4 inhibitor-associated BP, even after withdrawal of these drugs.

Acute basilar artery occlusions (BAO) that are not quickly recanalised may leave the patient with severe motor detriment. Efficacies of current treatments remain unclear. In our case of a 47-year-old-man presenting with quadriparesis, MRI demonstrated bilateral pontine infarct. A year after mechanical thrombectomy, he was fully ambulant.