<div>There is huge potential for marine natural products to be combined with genomics, metabolomics and bioinformatics. There is a widely recognised supply issue, particularly with marine natural products whose compounds are only extracted in very small quantities. As whole genome sequencing and whole exome sequencing become Mining the genome for genes that produce these metabolites and overexpressing those could lead to a huge increase in yield obtained for valuable molecules. This begins with proposing a biosynthetic pathway for a discovered molecule, leading to identification of genes that are involved in that pathway. These metabolite-producing genes can then be overexpressed in bacterial models to produce high yields of said compound. Although this may be more difficult for more complex organisms such as sponges, it is thought that bacteria living in the sponge are responsible for a large amount of secondary metabolite production.&nbsp; 
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