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Antonino Ingargiola edited Introduction.tex
about 8 years ago
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%(\href{https://www.mozillascience.org/effective-code-review-for-journals}{Mills 2015})
%(\href{http://ivory.idyll.org/blog/2015-we-live-in-a-bubble.html}{Brown 2015} and \href{http://ivory.idyll.org/blog/on-code-review-of-scientific-code.html}{2013}).
Recently, Other disciplines have started tackling this issue
(cite http://biorxiv.org/content/early/2016/03/24/045104 once doi activated),
and even in the single-molecule field a few
recent publications have included
or presented
open source software
implementation for analysis of
methods used to analyze surface immobilized
single-molecule experiments~\cite{Bronson_2009,Greenfeld_2012, K_nig_2013}.
In the field of For freely-diffusing
smFRET, smFRET experiments, although it is common to find mention of
"code available from the authors upon request" in publications, there is a dearth
of such open source code, with, to our knowledge, the notable exception of a single
example~\cite{Murphy2014}.
To address this issue, we have developed FRETBursts,
an open source Python software for
the analysis of freely diffusing single-molecule FRET
bursts. measurement.
FRETBursts can be used, inspected and modified by anyone interested in using
state-of-the art smFRET analysis
method methods or implementing modifications or completely new techniques.
FRETBursts therefore represents an ideal platform
for quantitative comparison of different methods for smFRET burst analysis.
Technically, a strong emphasis has been given to the reproducibility of complete analysis
workflows. FRETBursts uses Jupyter Notebooks~\cite{Shen_2014},
...
in a document which is easy to share and execute.
To minimize the possibility of bugs being introduced inadvertently~\cite{Soergel_2015}
we employ modern software engineering techniques
such as unit testing and continuous
integration~\cite{Wilson_2014}. integration~\cite{Wilson_2014}
(cite http://biorxiv.org/content/early/2016/03/24/045104 once doi activated).
FRETBursts is hosted on GitHub~\cite{Blischak_2016,Prli__2012},
where users can write comments, report issues or contribute code.
In a related effort, we recently introduced Photon-HDF5~\cite{Ingargiola2016},