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Eitan Lerner edited Abstract.tex
over 9 years ago
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Single-molecule FRET (smFRET) allows probing intermolecular interactions
and conformational changes in biomacromolecules, and represent an
invaluable tool in studying cellular processes
on at the molecular
scale~\cite{Kapanidis_2006}. smFRET experiments can detect the distance between
two fluorescent labels (\textit{donor} and \textit{acceptor}) in the
3-10~nm range. In the commonly employed confocal geometry, molecules are free