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Antonino Ingargiola Merge branch 'master' of https://github.com/tritemio/fretbursts_paper
about 8 years ago
Commit id: 5e5baa5ff37de835138bff31e7073088b4002956
deletions | additions
diff --git a/background-estimation.tex b/background-estimation.tex
index d857b2d..fa4b2cd 100644
--- a/background-estimation.tex
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...
The functions used to fit the background provide also a goodness-of-fit estimator
computed on the basis of the empirical distribution function (EDF)~\cite{Stephens1974,Parr1980}.
The ``distance'' between the EDF and the theoretical (i.e. exponential) cumulative distribution
represent represents and indicator of the quality of fit.
Two different distance metrics can be returned by the background fitting functions.
The first is the Kolgomorov-Smirnov statistics, which uses the maximum of the difference
between the EDF and the theoretical distribution. The second is the Cramér von Mises
...
(see the code for more details,
\href{https://github.com/tritemio/FRETBursts/blob/master/fretbursts/background.py#L41}{link}).
In principle, the optimal
interphoton-delay inter-photon delay threshold will minimize
the error metric. This approach is implemented by the function \verb|calc_bg_brute|
(\href{http://fretbursts.readthedocs.org/en/latest/plugins.html#fretbursts.burstlib\_ext.calc\_bg\_brute}{link}) which performs a brute-force search in order to find the optimal threshold.
This level of
sofistication sophistication in
estimation estimating the background rates is not
necessary under typical
circumstances, experimental conditions, as the difference between an optimal threshold
and a manually (or
euristically) choosen heuristically) chosen one
is will be small if not negligible in most practical cases.