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In this paper, we present a cloud-based analysis of the molecular emission in M83, searching for environmental variation in the cloud populations. In Section \ref{sec:data}, we present the ALMA data and report on the relevant limitations that affect our analysis. In Section \ref{sec:cprops}, we use the \citep{cprops} {\sc cprops}  algorithm \citep{Rosolowsky_2006} to decompose the molecular emission into the population of molecular clouds. We compare the properties of these clouds to the populations seen in the Milky Way and nearby galaxies. For comparison to the studies of clusters, we also analyze the mass distributions of the clouds. In Section \ref{sec:discussion}, we interpret the results of the analysis in terms of theoretical interpretations and the empirical results derived from cluster analysis.