this is for holding javascript data
Sean Maguire edited AIMS.md
about 11 years ago
Commit id: 71e7d8f991d626a0e47be769d968abac229ad345
deletions | additions
diff --git a/AIMS.md b/AIMS.md
index 0947b62..58c9345 100644
--- a/AIMS.md
+++ b/AIMS.md
...
##Chapter ###Chapter 1: Exploring how social status organizes the brain
###AIM ####AIM 1: To examine how the brain is organized over time following an opportunity to ascend in social status.
I will determine how functional networks change in the brain as animals transition from a subordinate (SUB) to a dominant (DOM) social status. I will then test how this process is impacted by SSH antagonists.
###AIM ####AIM 2: Examine how the animals respond to social challenge and opportunity at different stages of their transition.
I will expose transitioning animals to either a territorial challenge or a reproductive opportunity at different stages in their transition and examine cytochrome oxidase and egr-1 levels.
##Chapter ###Chapter 2: Community level consequences of social transition
###AIM ####AIM 1: To examine how the behavior of one individual can be transmitted throughout a social network (short term effects).
I will introduce a SUB male into a community where he is the largest male, disrupting the current dominance hierarchy. I will measure the social network as it changes over time, post introduction. One hour after the introduced male has gained DOM status, I will kill harvest the entire community and process their brains for in situ.
###AIM ####AIM 2: To examine how the behavior of one individual can be transmitted throughout a social network (long-term effects).
I will manipulate one individual DOM male with either estradiol antagonist or agonist which will cause him to become more or less aggressive. I will then monitor the social network. After 4 days I will kill the community members and use qPCR to examine expression of sex steroid hormone receptors cytochrome oxidase subunits from punches centered on different areas of the SDMN.