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Nobel prize winning ideas are not generally accepted by the community. By definition, they are paradigm shifting, revolutionary. Accordingly, many were first initially rejected by anonymous pre-publication peer review.
1. Nobel Prize Awarded awarded for: Identification of the mechanism for the synthesis of adenosine triphosphate (ATP)
Rejection: Boyer had been greeted with disbelief when he theorized that the previously mysterious process is the work of a "beautiful little machine" that operates within enzymes on the molecular level. His proposed resolution of a major unsolved problem in biochemistry threatened to "change the paradigm," Boyer remembers, and "the leading journal" in his field -The Journal of Biological Chemistry-declined to publish his work.
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