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Nobel prize winning ideas are not generally always accepted by the community. By definition, they are paradigm shifting, revolutionary. Accordingly, revolutionary.
Similarly, Werner Arber, the scientist who discovered restriction enzymes worked, "in a climate of almost total indifference, notably that of the committees and organizations tasked with allocating funds for research"
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keywords = {Molecular biology.},
pages = {158 p.},
year = {1998}
}" data-bib-key="b6c56a" contenteditable="false">Jacob 1998. Here we outline 8 Nobel prize papers that we initially rejected by anonymous pre-publication peer review and ask, "What Nobel ideas are we rejecting and/or delaying
today?"
1. Nobel Prize in Chemistry (1997) awarded to Paul Boyer for: Identification of the mechanism for the synthesis of adenosine triphosphate (ATP)
Rejection: Boyer had been greeted with disbelief when he theorized that the previously mysterious process is the work of a "beautiful little machine" that operates within enzymes on the molecular level. His proposed resolution of a major unsolved problem in biochemistry threatened to "change the paradigm," Boyer remembers, and "the leading journal" in his field -The Journal of Biological Chemistry-declined to publish his work.
today?"